Lead Scientist, E. coli Expression Systems

Initial Therapeutics, Inc.; Norwood (MA); On-site; USD 142,500 - 256,500; Full time

Benefits offered by this job

Best-in-class healthcare coverage

Family planning benefits

Generous paid time off

Savings and investment opportunities

Job summary

Initial Therapeutics, Inc. seeks a Principal Scientist, Process Development in Norwood, MA. The ideal candidate will lead strategies for microbial production, particularly focusing on E. coli. This role is centered on designing screening workflows, optimizing microbial expression, and driving process development.

To qualify, candidates need a PhD in Molecular Biology or a related field with substantial industry experience. The salary range for this position is $142,500 - $256,500, with additional benefits and support.

Qualifications

• PhD in Molecular Biology or relevant field with 5+ years relevant experience.
• Substantial experience with E. coli strain engineering and vector design.
• Hands-on expertise in developing microbial expression-screening workflows.

Responsibilities

• Own the strategy for E. coli host strain and expression system.
• Design and execute screening cascades to identify production candidates.
• Lead or support strain and vector engineering to improve expression performance.

Skills

E. coli strain engineering

Molecular biology

Expression-system design

Screening workflows

Data-driven approaches

Education

PhD in Molecular Biology or related field

MS with 10+ years experience

BS with 12+ years experience

Tools

High-throughput screening systems

Data analysis tools

Job description

Initial Therapeutics, Inc. seeks a Principal Scientist, Process Development in Norwood, MA. The ideal candidate will lead strategies for microbial production, particularly focusing on E. coli. This role is centered on designing screening workflows, optimizing microbial expression, and driving process development.

To qualify, candidates need a PhD in Molecular Biology or a related field with substantial industry experience. The salary range for this position is $142,500 - $256,500, with additional benefits and support.