Lead Principal Investigator - Early-Phase Clinical Trials

Pharmaron Beijing Co. Ltd.; Baltimore (MD); On-site; USD 200,000 - 285,000; Full time

Benefits offered by this job

Medical, Dental & Vision Insurance

401(k) Retirement Plan

Paid Time Off

Health Savings Account contributions

Life Insurance

Employee Assistance Program

Fertility resources

Professional development

Job summary

Pharmaron is seeking a Principal Investigator to lead early-phase clinical trials in Baltimore, MD, onsite. This role provides medical leadership, participant safety oversight, and collaboration with sponsors and internal teams to drive study success.

Ideal candidates hold an MD/DO with board certification and an active license, plus 5+ years of clinical practice. Experience in Phase I/early development and FDA/ICH-GCP familiarity are preferred.

Qualifications

• MD or DO degree from an accredited medical school
• Board Certification in a recognized specialty
• Active and unrestricted medical license
• Minimum 5 years of clinical practice experience
• Current CPR and ACLS certifications
• Strong understanding of patient care, medical ethics, and clinical decision-making
• Excellent communication and leadership skills

Responsibilities

• Serve as Principal Investigator or Sub-Investigator for Phase I-III clinical studies
• Provide medical oversight and ensure participant safety throughout study conduct
• Review eligibility, medical histories, adverse events, and safety data
• Conduct physical examinations and medical assessments as required
• Partner with sponsors and internal teams on protocol review, study design, and implementation
• Support dosing activities and ongoing medical monitoring
• Contribute to study interpretation, reporting, and regulatory submissions
• Provide scientific and medical consultation to project teams and clients
• Ensure studies are conducted in compliance with ICH-GCP, FDA regulations, and applicable guidelines
• Maintain protocol integrity and oversight responsibilities as listed on FDA Form 1572
• Support inspections, audits, and regulatory interactions when required
• Mentor and guide Clinical Research Coordinators, nurses, and study staff
• Promote a culture of participant safety, quality, and operational excellence
• Collaborate closely with Medical, Clinical Operations, Pharmacy, Laboratory, and Business Development teams

Skills

MD/DO

Board Certified

Medical license

Clinical experience

CPR/ACLS

Communication

Leadership

Education

MD/DO degree

Job description

Pharmaron is seeking a Principal Investigator to lead early-phase clinical trials in Baltimore, MD, onsite. This role provides medical leadership, participant safety oversight, and collaboration with sponsors and internal teams to drive study success.

Ideal candidates hold an MD/DO with board certification and an active license, plus 5+ years of clinical practice. Experience in Phase I/early development and FDA/ICH-GCP familiarity are preferred.