Lead DDR Scientist—Heavy Particle Radiobiology

Mayo Foundation for Medical Education and Research; Jacksonville (FL); On-site; USD 180,000 - 260,000; Full time

Benefits offered by this job

Retirement benefits

Pension programs

Collaborative environment

Job summary

Mayo Clinic Florida invites applications for an open-rank faculty position focusing on DNA damage repair and response pathways, especially in heavy particle therapies like proton and carbon ion radiotherapy, in animal models and clinical studies. The role aims to expand a multidisciplinary program in radiation biology and oncology.

The successful candidate will lead innovative research, integrate with a global technology collaboration, and advance clinical translation through discovery science

Qualifications

• Qualified candidates must hold a doctoral degree in genetics, molecular biology, radiation biology, biomedical engineering, or related discipline.
• Strong record of high-impact publications in DNA damage response and radiobiology.
• Sustained extramural funding appropriate to academic rank.
• Demonstrated scientific leadership and ability to build multidisciplinary programs.
• Commitment to mentorship, education, and fostering an inclusive culture.

Responsibilities

• Characterize cellular and molecular responses to photon, proton, and heavy-ion radiation.
• Identify DNA repair pathway choices and map DDR vulnerabilities for patient stratification or co-targeting.
• Develop preclinical models to test synergy between radiotherapy and targeted therapy.
• Drive discoveries in neo-antigen discovery and combination immunotherapy related to DNA damage.
• Provide mechanistic insights to support clinical translation of carbon-ion-based treatment programs.
• Collaborate with computational scientists to identify clinical vulnerabilities and model radiation-response signatures.

Skills

DDR pathways

Radiobiology

Leadership

Mentorship

Education

Doctoral degree in genetics, molecular biology, radiation biology, biomedical engineering, or related discipline

Job description

Mayo Clinic Florida invites applications for an open-rank faculty position focusing on DNA damage repair and response pathways, especially in heavy particle therapies like proton and carbon ion radiotherapy, in animal models and clinical studies. The role aims to expand a multidisciplinary program in radiation biology and oncology.

The successful candidate will lead innovative research, integrate with a global technology collaboration, and advance clinical translation through discovery science