Lead, Computational Drug Discovery & AI Innovation

Zealand Pharma; Cambridge (MA); On-site; USD 223,000 - 300,000; Full time

Job summary

Zealand Pharma invites a Senior Director, Computational Drug Discovery, to lead a global team across Cambridge, MA and Copenhagen, DK. You will set vision, drive computational strategy, and advance multi-modal pipeline decision making through in-silico methods, collaboration with chemistry, biology, and DMPK teams, and AI-driven initiatives.

The role emphasizes building capabilities, guiding programs, and shaping an innovation-focused culture while delivering pipeline impact at Zealand.

Qualifications

• Ph.D. (or equivalent) in Computational Chemistry/Biology/Structural Biology or a life sciences discipline.
• 10+ years of biopharma R&D experience.
• Ability to lead and mentor a global team across two sites.

Responsibilities

• Mentor and grow a global computational drug discovery team across two sites (Cambridge, USA and Copenhagen, DK).
• Lead and drive computational strategy to support a multi-modal pipeline including peptides, small molecules and antibodies.
• Contribute to AI strategy, FAIR data foundations, MLops, and integration of foundation models and LLMs.

Skills

Structure prediction

Structure modeling

Generative design

Drug design

Pharmacology

Leadership

Education

Ph.D. in Computational Chemistry/Biology/Structural Biology

Tools

LLMs

MLops

Job description

Zealand Pharma invites a Senior Director, Computational Drug Discovery, to lead a global team across Cambridge, MA and Copenhagen, DK. You will set vision, drive computational strategy, and advance multi-modal pipeline decision making through in-silico methods, collaboration with chemistry, biology, and DMPK teams, and AI-driven initiatives.

The role emphasizes building capabilities, guiding programs, and shaping an innovation-focused culture while delivering pipeline impact at Zealand.