Lead Bioseparation Scientist - Analytical Dev for Biologics

Element Materials Technology; Ann Arbor (MI); On-site; USD 100,000 - 140,000; Full time

Job summary

Element Materials Technology is seeking a Principal Scientist - Bioseparation & Analytical Development in Ann Arbor, MI. This role involves leading advanced analytical method development for large molecule therapeutics in a laboratory setting. Candidates should have a PhD and extensive experience in biopharmaceutical analysis, particularly with chromatography and mass spectrometry techniques. The position emphasizes innovative scientific approaches and offers mentorship opportunities in a collaborative environment.

Qualifications

• 8-15+ years of experience in biopharmaceutical or CRO analytical development with strong hands-on expertise.
• Demonstrated experience in comparability, stability studies, and degradation pathway analysis for complex biologics.
• Strong scientific writing capability with experience supporting regulatory documentation and submissions.

Responsibilities

• Lead development, optimization, and troubleshooting of bioseparation-based analytical methods.
• Ensure development of robust GMP-compliant methods aligned with ICH Q2/Q6.
• Drive innovation in analytical science, including implementation of high-throughput LC-MS platforms.

Skills

Chromatography Platforms

Mass Spectrometry

Bioseparation Sciences

Analytical Method Development

Protein Characterization

Education

PhD in Analytical Chemistry, Biochemistry, Pharmaceutical Sciences, or related field

Tools

HPLC

UPLC

LC-MS/MS

CE-SDS

SEC-MALS

Job description

Element Materials Technology is seeking a Principal Scientist - Bioseparation & Analytical Development in Ann Arbor, MI. This role involves leading advanced analytical method development for large molecule therapeutics in a laboratory setting. Candidates should have a PhD and extensive experience in biopharmaceutical analysis, particularly with chromatography and mass spectrometry techniques. The position emphasizes innovative scientific approaches and offers mentorship opportunities in a collaborative environment.