Lead, Biological Systems Modeling & Predictive Analytics

Battelle; North Carolina; Hybrid; USD 128,800 - 183,600; Full time

Benefits offered by this job

Hybrid work arrangement

Compressed work schedule

Paid time off

401(k) retirement plan

Tuition assistance

Job summary

Battelle seeks a Technical Lead - Biological Systems Modeling Analytics in a hybrid setup, located in Columbus, OH. Lead development of computational toxicology models, ML analytics, and multi-scale simulations across biology and chemistry domains.

Requires a Ph.D. and 8+ years in computational modeling with strong programming (Python, R, MATLAB). Collaboration with scientists and engineers is essential for federal health program solutions.

Qualifications

• Ph.D. in computational biology, bioinformatics, physics, chemistry, applied mathematics, or related field
• 8+ years of experience in computational modeling, data science, or quantitative biology
• Demonstrated experience in computational toxicology, bioinformatics, or related domain
• Expertise in statistical modeling and machine learning; differential equation-based modeling (ODE/PDE/stochastic); Bayesian methods and probabilistic modeling

Responsibilities

• Develop and implement computational toxicology models, including PBPK/PBTK and qAOP frameworks
• Design and apply ML and statistical models to classify, cluster, and predict toxicity of chemical compounds using large-scale datasets (e.g., Tox21, bioactivity data)
• Build multi-scale models using differential equations (ODE/PDE), stochastic processes, and Bayesian methods
• Apply advanced analytics techniques, including multivariate analysis, dimensionality reduction, and probabilistic inference
• Develop algorithms for pattern recognition, classification, and predictive modeling across biological and chemical datasets
• Collaborate with multidisciplinary teams including biologists, toxicologists, statisticians, and software engineers
• Translate complex scientific outputs into clear, actionable insights and technical deliverables
• Support proposal development and technical solutioning for federal health and environmental programs (e.g., CDC, NIH, FDA, EPA)
• Mentor junior staff and contribute to development of scientific and analytic capabilities across the team

Skills

Python

R

Machine learning

Statistical modeling

Differential equations modeling

Bayesian methods

Security clearance eligibility

Education

Ph.D. in computational biology / bioinformatics / physics / chemistry / applied mathematics

Tools

MATLAB

Job description

Battelle seeks a Technical Lead - Biological Systems Modeling Analytics in a hybrid setup, located in Columbus, OH. Lead development of computational toxicology models, ML analytics, and multi-scale simulations across biology and chemistry domains.

Requires a Ph.D. and 8+ years in computational modeling with strong programming (Python, R, MATLAB). Collaboration with scientists and engineers is essential for federal health program solutions.