Lead Bioinformatician for Neurodegeneration & Multi-Omics

University of Michigan; Ann Arbor (MI); Hybrid; USD 120,000 - 190,000; Full time

Job summary

University of Michigan seeks a Bioinformatician/Computational Biologist Lead to direct and conduct analyses for neurodegeneration research, focusing on ALS and diabetes-related neuropathies. You will design workflows for bulk and single-cell sequencing, integrate multi-omics data, and model disease progression.

Lead the lab's computational program and collaborate with core facilities and investigators. You will co-author publications and grants while mentoring analysts, contributing to

Qualifications

• Advanced degree in Bioinformatics or related field with 10+ years in high-throughput data analysis.
• Experience designing transcriptomics studies and multi-omics data integration.
• Publication record in peer-reviewed journals is essential.
• Experience supervising analysts and coordinating data workflows.

Responsibilities

• Direct the laboratory's bioinformatics analysis function and set priorities across studies.
• Design and conduct analyses for neurodegeneration using RNA-Seq, scRNA-Seq, and multi-omics data.
• Collaborate with core facilities and investigators; train researchers on bioinformatics tools.
• Develop reproducible workflows, manage software, storage, and cloud resources.
• Co-author publications and grant proposals; present results at conferences.

Skills

Bioinformatics

RNA-Seq

Single-cell

Python

R

Education

Masters or PhD in Bioinformatics

Tools

Bioconductor

GATK

Seurat/Scanpy

IGV

Nextflow

Snakemake

Git

Job description

University of Michigan seeks a Bioinformatician/Computational Biologist Lead to direct and conduct analyses for neurodegeneration research, focusing on ALS and diabetes-related neuropathies. You will design workflows for bulk and single-cell sequencing, integrate multi-omics data, and model disease progression.

Lead the lab's computational program and collaborate with core facilities and investigators. You will co-author publications and grants while mentoring analysts, contributing to