Lab Analyst II NENSP Molecular

UMass Med School; Worcester (MA); On-site; USD 65,000 - 80,000; Full time

Job summary

UMass Medical School in Worcester, MA seeks a Lab Analyst II NENSP Molecular to perform molecular assays for newborn disorder screening. The role requires experience with high-complexity testing under supervision and adherence to established protocols.

Responsibilities include bench work, assay development, validation, instrument management, and data recording for quality assurance. A strong background in molecular biology and CLIA-compliant work is essential.

Qualifications

• Bachelor's degree or equivalent in chemical, life or clinical sciences.
• College-level coursework or equivalent yielding a solid understanding of molecular biology.

Responsibilities

• Performs laboratory assays (clinical or research) with documentation as part of the section's analysts, following validated protocols.
• Follows established safety and privacy protocols.
• Performs bench work to assist management in validation, development, and troubleshooting of laboratory assays and kit procedures.
• Assists in validation, troubleshooting, and management of instrumentation used in screening procedures.
• Supports validation and monitoring of instrument relationships with the Laboratory Information Management System.
• Contributes to the preparation and validation of reagents, materials and kits used in the laboratory.
• Provides data for quality assurance, quality control, and competency records per CLIA requirements.
• Performs other duties as required.

Education

Bachelor's degree or equivalent in chemical, life or clinical sciences

Job description

Lab Analyst II NENSP Molecular

Job Details

• Requisition Number: 2026-50398
• # of Openings: 1
• Posted Date: Day
• Shift: Non Exempt
• Exempt/Non-Exempt Status: Non Union Position-W25-Non Unit Classified
• Position Type: Full-Time

Job Location

US-MA-Worcester

2 hours ago (7/30/2026 10:40 AM)

Minimum Salary

USD $65,000.00/Yr.

Max

USD $80,000.00/Yr.

Overview

Under the general supervision of Lab Management, the Lab Analyst II NENSP Molecular performs laboratory assays for the timely detection of newborn disorders. Maintains competency in high complexity testing (as defined by CLIA) in all molecular methodologies used in the section. Performs other related laboratory tasks in support of laboratory management. Responsibilities include careful adherence to established laboratory protocols, or specific directives of appropriate laboratory managers. This is an intermediate level laboratory position that requires previous relevant laboratory experience and will work under a moderate level of direction and supervision to perform assigned work.

Responsibilities

• Performs laboratory assays (clinical or research) with appropriate documentation, as an integral member of the section's laboratory analysts, following validated protocols.
• Follows established safety and privacy protocols.
• Performs bench work to assist management in the performance and documentation of laboratory activities for the technical development, validation, performance and troubleshooting of laboratory assays (both laboratory-developed tests as well as kit assays) used in the screening procedures.
• Performs bench work to assist management in laboratory activities for validation, troubleshooting the performance of and management of instrumentation used in the screening procedures.
• Performs bench work to assist management in laboratory activities for validation, troubleshooting and monitoring of the instrumentation relationships with Laboratory Information Management System.
• Works as an integral team member as needed in the preparation and validation of reagents, materials and kits used in the laboratory.
• Contributes data for laboratory documentation of quality assurance, quality control, and competency data in accordance with Program policies and CLIA requirements.
• Perform other duties as required.

Qualifications

REQUIRED EDUCATION

• Bachelor's degree or equivalent in chemical, life or clinical sciences
• College-level coursework or equivalent yielding a solid understanding of the theory of molecular biology

REQUIRED WORK EXPERIENCE

• 1 - 5 years of relevant experience including some previous clinical laboratory experience
• 2 - 5 years of Assay Implementation and Troubleshooting experience
• Experience with several of the following: Primer Design, Probe Design, LNA design, Multiplex RealTime PCR design, Nested PCR design, copy-number assay design in relation to
• Experience in the clinical application of PCR-based assays, inclusive of the prevention and containment of amplicon contaminants
• Experience in the implementation of clinical detection systems for the generation of human genotypic data using a variety of techniques (Luminex Lab developed tests, Real-Time lab developed tests)
• Experience in the implementation of clinical assays for the evaluation of the presence/absence and quantification of molecular markers (RealTime and Digital Droplet PCR or equivalent).
• 2 - 5 years of Implementation of High-throughput Clinical Molecular Assays experience
• Practical experience in the isolation of nucleic acids from small-volume (3 L) dried blood spots or other similar human specimens.
• Expertise in high-throughput processing of clinical specimens
• Experience with robotics applications for high-throughput processing of clinical specimens
• 1 - 3 years of experience with specialized assays such as sequencing or human identity testing
• 1 - 3 years of experience in database and spreadsheet applications for quality monitoring
• Must satisfy CLIA requirements for high complexity testing
• Experience with standard concepts, practices, and procedures within the clinical laboratory
• Good communication and organizational skills, with focus on detail and orderliness
• Ability to perform laboratory procedures independently once trained, with great care and attention
• Strong interpersonal skills
• Experience with productivity software (Excel, Word, Access)
• Flexibility in work schedule as required by laboratory section (i.e., weekend and holiday rotations).

PREFERRED WORK EXPERIENCE

• Experience
• Experience with standard concepts, practices, and procedures within the field of emerging technologic analyses
• Experience in the development of PCR-based assays, inclusive of the prevention and containment of amplicon contaminants
• Experience in the development of clinical detection systems for the generation of human genotypic data using a variety of techniques (Luminex Lab developed tests, Real-Time lab developed tests)
• Experience in the development of clinical assays for the evaluation of the presence/absence and quantification of molecular markers (RealTime and Digital Droplet PCR or equivalent).
• Experience with Sanger sequencing and related informatics