In Vivo Neuroscience Postdoc: Circuitry & Behavior

100 Eli Lilly and Company; Indianapolis (IN); On-site; USD 58,000 - 123,000; Full time

Job summary

The Psychiatry and Neuronal Health group at Eli Lilly is seeking a highly motivated Postdoctoral Research Fellow to join an active in vivo pharmacology program focused on reward, arousal, and stress-related neural circuitry.

The role involves designing and executing in vivo rodent experiments, including self-administration, extinction, cue reinstatement, and fiber photometry recordings, with strong emphasis on data integration and publication.

Qualifications

• PhD in Neuroscience, Pharmacology, Behavioral Neuroscience, or closely related field.
• Hands-on in vivo fiber photometry experience with calcium/neuropeptide sensors.
• Stereotaxic surgery, viral vectors, and fiber optic cannula implantation expertise.
• Experience with operant/behavioral pharmacology models (IV self-administration, extinction, cue reinstatement).
• Familiarity with microdialysis and downstream quantification (HPLC/LC-MS).
• Authorized to work in the United States full-time.

Responsibilities

• Design and execute in vivo experiments in rodent models relevant to CNS drug discovery.
• Perform rodent survival surgeries: stereotaxic viral injections and catheter implantation.
• Conduct fiber photometry recordings to characterize circuit dynamics during behavior.
• Measure neurotransmitter efflux using microdialysis and LC-MS.</br>
• Map projections and test causal role in behaviors; perform histology.
• Support processing of human brain tissue and coordinate with repositories.
• Analyze multimodal datasets and document data rigorously.
• Prepare manuscripts and present findings at meetings and conferences.

Skills

In vivo fiber photometry

Rodent stereotaxic surgery

Operant/behavioral pharmacology

Data analysis (MATLAB/Python/R)

Publication track record

Excellent communication

Education

PhD in Neuroscience or related field

Tools

Fiber photometry hardware

HPLC/LC-MS

Viral vectors & stereotaxic equipment

Job description

The Psychiatry and Neuronal Health group at Eli Lilly is seeking a highly motivated Postdoctoral Research Fellow to join an active in vivo pharmacology program focused on reward, arousal, and stress-related neural circuitry.

The role involves designing and executing in vivo rodent experiments, including self-administration, extinction, cue reinstatement, and fiber photometry recordings, with strong emphasis on data integration and publication.