IHC Laboratory Manager

Pfm; Houston (TX); On-site; USD 110,700 - 166,100; Full time

Benefits offered by this job

Health insurance

Retirement savings benefits

Discretionary annual bonus

Paid time off

Job summary

Pfm is seeking a Laboratory Manager to oversee operations in a high-complexity clinical laboratory in Houston, Texas. This role involves ensuring scientific excellence and compliance in IHC and FISH testing and managing laboratory personnel.

The ideal candidate will have at least 8 years of experience in a clinical setting, a relevant degree, and leadership skills. Benefits include health insurance, a retirement plan, and a discretionary annual bonus.

Qualifications

• 8+ years of industry experience in a clinical, diagnostic, or CRO laboratory.
• 2+ years of leadership experience in a CAP- or CLIA-regulated laboratory.
• ASCP certification (HT or equivalent) required.

Responsibilities

• Oversee IHC and FISH analyses and support assay development.
• Manage testing personnel and ensure adherence to guidelines.
• Ensure accurate sample tracking and documentation.

Skills

Leadership

Regulatory compliance

Analytical instruments operations

Organizational skills

Time management

Communication skills

Education

Bachelor’s degree in Biology, Chemistry, or related field

Tools

Microsoft Office Suite

Job description

Position Summary

The Laboratory Manager is responsible for overseeing the daily operations of a high-complexity clinical and/or translational laboratory within a CAP/CLIA-regulated environment. This role ensures scientific excellence, regulatory compliance, and operational efficiency across Immunohistochemistry (IHC) and Fluorescence In Situ Hybridization (FISH) testing.

In a Contract Research Organization (CRO) setting, the Laboratory Manager partners closely with cross-functional teams to support client-driven projects, clinical trials, and biomarker development efforts.

Essential functions of the job

• Oversee IHC and FISH analyses, support assay development, and cross-train laboratory personnel on regulated IHC and FISH SOPs
• Manage testing personnel and ensure adherence to CAP/CLIA and GxP guidelines relevant to each assay/study
• Develop and manage staff schedules, including rotation and holiday coverage; serve as backup for laboratory testing as needed
• Ensure laboratory procedures are performed in accordance with SOPs by appropriately trained personnel; address deviations promptly and report issues to management and QA
• Ensure accurate sample tracking and testing documentation within LIMS
• Monitor and report KPIs, including turnaround time (TAT), quality event investigations and closures, staff capacity, and special project progress
• Maintain proficiency in laboratory operations by completing training on all relevant SOPs
• Oversee laboratory equipment and workspaces to ensure they are clean, well-maintained, and fully operational
• Recommend equipment replacement or maintenance based on performance and notify management/QA of any issues
• Monitor inventory of laboratory supplies, reagents, and consumables; order and replenish as needed
• Identify opportunities to improve efficiency and reduce laboratory supply costs
• Maintain competency across applicable assays and serve as backup testing personnel when necessary
• Drive efficient use of time, resources, and equipment
• Evaluate and improve laboratory procedures; provide recommendations to management
• Perform other duties as assigned

Qualifications

Minimum Required

• Bachelor’s degree in Biology, Chemistry, or a related scientific field
• 8+ years of industry experience in a clinical, diagnostic, or CRO laboratory, including hands‑on IHC assay experience
• 2+ years of leadership experience in a CAP- or CLIA-regulated laboratory
• ASCP certification (HT or equivalent)

Other Required

• Strong organizational and time management skills
• Ability to work independently and make decisions with minimal supervision
• Experience operating analytical instruments commonly used in laboratory settings
• Proficiency in Microsoft Office (Word, Excel, PowerPoint)
• Strong communication and interpersonal skills, with the ability to directly supervise staff
• Demonstrated sound judgment and discretion
• Ability to read, write, and speak English fluently
• Willingness to work extended hours, including evenings, weekends, and holidays, and occasional travel as required to support business and scientific objectives

Preferred

• Specialized knowledge in biochemistry, immunology, molecular biology, or cell biology

Compensation

Reasonable estimate of the current range: $110,700—$166,100 USD. This compensation range takes into account the wide range of factors that are considered in making compensation decisions including but not limited to: skill sets, experience and training, licensure and certifications, and other business and organizational needs. The disclosed range estimate has not been adjusted for the applicable geographic differential associated with the location at which the position may be filled. At Precision, it is not typical for an individual to be hired at or near the top of the range for their role and compensation decisions are dependent on the facts and circumstances of each case. This role is also eligible for a discretionary annual bonus, health insurance, retirement savings benefits, life insurance and disability benefits, parental leave, and paid time off for sick leave and vacation, among other benefits.

Legal Notice

Any data provided as a part of this application will be stored in accordance with our Privacy Policy. For CA applicants, please also refer to our CA Privacy Notice.

Precision Medicine Group is an Equal Opportunity Employer. Employment decisions are made without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status or other characteristics protected by law.

If you are an individual with a disability and require a reasonable accommodation to complete any part of the application process or are limited in the ability or unable to access or use this online application process and need an alternative method for applying, you may contact Precision Medicine Group at [e-mail].

Recruitment Fraud Warning: Please be aware that fraudulent individuals and websites may impersonate Precision Medicine Group or its affiliates and attempt to obtain personal, financial, or banking information through fake job postings or employment offers. Precision Medicine Group will never request payment, banking details, or other sensitive financial information as part of the recruitment process. If you believe you have been targeted by a recruitment scam, we encourage you to report the incident to your local law enforcement authorities, consumer protection agency, or relevant cybercrime reporting organization in your country. Please also notify us at [e-mail] so we can investigate and take appropriate action.