Hybrid InfoSec & Technology Program Manager Seattle

A-Alpha Bio; United States; Hybrid; USD 135,000 - 169,000; Full time

Benefits offered by this job

Competitive compensation

Flexible time off

Equity in a fast-growing startup

Job summary

A-Alpha Bio is seeking a Manager, Information Security & Technology to own and lead our information security and technology program, including security, cloud, lab tech, and governance. The role requires direct ownership and vendor management, not delegation to a team.

The position reports to the VP, Finance & Operations and offers a hybrid work model with relocation to Seattle, WA. Starting salary range is $135,000–$169,000 per year and is exempt.

Qualifications

• Bachelor’s degree in a related field with 7 years of experience in IT, cybersecurity, cloud administration, or technology operations.
• Hands-on experience administering and securing AWS cloud environments, Microsoft 365, and Entra ID.
• Experience implementing and operating a cybersecurity program aligned with the NIST Cybersecurity Framework (or comparable), including risk management, vulnerability remediation, governance, and vendor and MSP oversight.
• Experience leading cross-functional cybersecurity, cloud, and infrastructure initiatives end-to-end through influence and technical expertise.
• Ability to communicate technical concepts and risks to technical and non-technical audiences.
• Strong writing skills in regards to policies, executive summaries, and customer-facing security responses.
• Ability to develop pragmatic, fit-for-purpose solutions that balance security, laboratory, scientific, and business needs.

Responsibilities

• Own the company’s cybersecurity program and NIST-aligned roadmap.
• Maintain security policies and procedures, control reviews, and corrective actions.
• Manage risk assessments, penetration testing, and vulnerability remediation.
• Develop security metrics, risk reporting, and executive dashboards.
• Coordinate awareness and phishing training; support customer security reviews and questionnaires.
• Lead AWS infrastructure and security improvements from risk assessments and operational reviews.
• Manage cloud identity, access, encryption, logging, and monitoring.
• Support disaster recovery and business continuity, partnering with Data Science on secure cloud environments.
• Own office and laboratory network security and architecture.
• Assess, design, and implement network segmentation between corporate and laboratory environments.
• Manage firewalls, DNS, secure connectivity, and network access controls.
• Support lab device and instrument integration, partnering with the MSP on reliable infrastructure.
• Administer Microsoft 365 and Entra ID, including Conditional Access, Intune, identity governance, and endpoint security.
• Manage application registrations, enterprise applications, user provisioning, and privileged access reviews.
• Own administration and governance of key SaaS and enterprise applications with business owners, including access, licensing, integrations, and vendor escalations.
• Coordinate response to application outages and service issues.
• Establish AI governance and secure-use standards, including an inventory of approved AI tools and platforms.
• Review technology vendors and SaaS applications for security risks.
• Own MSP and security vendor relationships, performance, and accountability.
• Lead technology, infrastructure, and security projects end-to-end, coordinating changes organization-wide.
• Develop a multi-year technology roadmap and recommend investments in security, efficiency, and scalability.

Skills

Cybersecurity leadership

AWS administration

Microsoft 365

Entra ID

NIST framework

Risk management

Vendor/MSP oversight

Communication

Policy writing

Cloud security

Education

Bachelor's degree in a related field

Tools

AWS security tools

MS 365 security controls

Networking security

Job description

A-Alpha Bio is seeking a Manager, Information Security & Technology to own and lead our information security and technology program, including security, cloud, lab tech, and governance. The role requires direct ownership and vendor management, not delegation to a team.

The position reports to the VP, Finance & Operations and offers a hybrid work model with relocation to Seattle, WA. Starting salary range is $135,000–$169,000 per year and is exempt.