Histology Technician or Histotechnologist (HT/HTL) - Anatomic Pathology

Mayo Clinic; Oronoco (MN); On-site; USD 37,000 - 54,000; Full time

Benefits offered by this job

Medical plans

Dental coverage

Vision plan

HSA/FSAs

Retirement plan

Job summary

Mayo Clinic is seeking Histology Technicians and Histotechnologists (HT/HTL) to join our Anatomic Pathology team. Roles span Histology, Frozen Section, IHC, and Renal Pathology across multiple labs, processing high volumes of specimens to support accurate diagnoses. Start dates require HT/HTL credentials and ASCP certification by start date.

The Laboratory offers diverse workflows, strong teamwork, and opportunities for professional growth within Mayo Clinic’s renowned pathology network.

Qualifications

• Associate degree requirement (HT).
• Bachelor's degree required (HTL).
• ASCP certification required by start date.

Responsibilities

• Prepare high-quality microscopic slide preparations for pathologists.
• Embed specimens and perform microtomy for sections.
• Perform cryotomy and special stains, IHC, and ISH.
• Handle fresh and complex specimens with attention to quality.

Skills

Attention to detail

Team collaboration

Education

Associate degree in Histology

Bachelor's degree in Histology

Tools

ASCP certification

Job description

Why Mayo Clinic

Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans (benefits/) - to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.

Benefits Highlights

• Medical: Multiple plan options.
• Dental: Delta Dental or reimbursement account for flexible coverage.
• Vision: Affordable plan with national network.
• Pre-Tax Savings: HSA and FSAs for eligible expenses.
• Retirement: Competitive retirement package to secure your future.

Responsibilities

Mayo Clinic is seeking Histology Technicians and Histotechnologists (HT/HTL) to join a dynamic and collaborative team within Anatomic Pathology. Opportunities are available across multiple specialized laboratory areas, including:

• Histology
• Frozen Section/Surgical Pathology
• Immunohistochemistry (IHC)
• Renal Pathology

Each lab is offering unique workflows, techniques, and clinical impact.The Anatomic Pathology Laboratories at Mayo Clinic process a high volume of complex specimens, including hundreds of thousands of paraffin-embedded blocks and over one million slides annually. Specimens include surgical, autopsy, and research material. Our laboratories take pride in contributing to accurate patient diagnoses and advancing scientific knowledge through collaboration with pathologists, clinicians, and research investigators.Visit the Clinical Labs career site (clinicallabs) to watch a brief video of Dane discussing a life-changing career in Histology at Mayo Clinic.

As an HT/HTL, you will play a critical role in preparing high-quality slides for pathologist review. Responsibilities may include embedding, microtomy, cryotomy, special staining, immunohistochemical techniques, and handling of fresh and complex specimens. The work requires attention to detail, adaptability, and a commitment to quality and patient care.

In addition, you will:

• Support training and onboarding of students and new employees
• Collaborate across multidisciplinary teams to ensure timely and accurate results
• Contribute to a respectful, inclusive, and team-oriented work environment
• Adapt to the unique demands and workflows of different subspecialty laboratories

Mayo Clinic offers extensive opportunities for professional growth and career advancement within Anatomic Pathology. Whether you are interested in developing technical expertise across multiple lab areas or specializing in a particular discipline, this role provides a strong foundation for long-term career development.

Histology Technician / Histotechnologist (HT/HTL)

As a Histology Technician or Histotechnologist, you will perform a variety of technical procedures to prepare high-quality microscopic slide preparations used by pathologists for diagnostic and prognostic evaluation. These procedures may include:

• Specimen accessioning and identification
• Specimen processing and embedding
• Microtomy techniques, including:
• Paraffin
• Frozen (cryotomy)
• Plastic sections
• Routine Hematoxylin and Eosin (H&E) staining
• Special stains
• Immunofluorescence
• Immunohistochemical (IHC) staining
• In situ hybridization
• Individuals hired to this position are required to complete 2 years in this position before becoming eligible to apply to other positions within Mayo Clinic.**These positions are ineligible for visa sponsorship. Also, Mayo Clinic DOES NOT participate in the F-1 STEM OPT extension program**

Qualifications

Histology Technician (HT) :

• Associate degree required.
• Coursework including 24 semester hours of the following:
• A minimum of 12 credit hours in chemistry, biology, or medical laboratory technology
• 6 credit hours in chemistry
• 6 credit hours in biology
• Histology Technician (HT) certified by the American Society of Clinical Pathologists (ASCP) required by start date

Histotechnologist (HTL) :

• Bachelor's degree required.
• Histotechnologist (HTL) certified by the American Society of Clinical Pathologists (ASCP) required by start date

Additional Qualifications

• Graduate of a NAACLS accredited program preferred.
• Graduates of the Mayo Clinic School of Health Sciences Histology Technician Program will receive preference.
• Ability to accommodate scheduling adjustments, off shifts, holidays, on-call, and weekend work assignments.
• Employees obtaining certification(s) after January 1, 2004, will be required to demonstrate evidence of ongoing maintenance of certification.

Exemption Status

Nonexempt

Compensation Detail

The pay range for Histology Technician is $26.52 - $39.32 per hour. The pay range for Histotechnologist is $32.43 - $48.66 per hour.

Benefits Eligible

Yes

Schedule

Full Time

Hours/Pay Period

80

Schedule Details

Varies

Weekend Schedule

Varies

International Assignment

No

Site Description

Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is. (alllocations)

Equal Opportunity

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law" (poster) . Mayo Clinic participates in E-Verify () and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.