Histology Technician/Histotechnologist - Immunohistochemistry

ccf; Cleveland (OH); On-site; USD 52,000 - 76,000; Full time

Benefits offered by this job

Sign-on bonus

Job summary

Cleveland Clinic Health System is seeking a Histology Technician/Histotechnologist for an evening shift at the Cleveland Clinic Main Campus. You will process tissue specimens, perform histology stains, and support pathologists with accurate preparation of samples for diagnosis.

Eligible for a $5,000 sign-on bonus. Candidates may have ASCP HT/HTL eligibility, a bachelor’s degree, and experience in immunohistochemistry. Join a leading healthcare system committed to excellence and patient care.

Qualifications

• ASCP Certification eligible in Histology
• One year of experience preferred
• Bachelor’s degree or CLIA qualifications for Histotechnologist (HTL) or related

Responsibilities

• Prepare, process, embed, and section tissue specimens using histology equipment (microtomes, cryostats)
• Perform routine and specialized staining procedures including histochemical and enzyme stains
• Mount, label, and distribute slides for pathologist review
• Maintain laboratory equipment and coordinate repairs
• Prepare reagents, buffers, and solutions to support testing procedures
• Document patient and specimen data and maintain records
• Ensure cleanliness and QC of lab instruments and workspaces
• Assist training and serve as a resource for students and residents
• Perform immunohistochemical and in-situ hybridization procedures as applicable

Skills

Histology

Immunohistochemistry

Education

Bachelor’s degree or HT/HTL eligible

ASCP HT/HTL certification eligible

Tools

Microtomes

Cryostats

Stains

Automation

Job description

At Cleveland Clinic Health System, we believe in a better future for healthcare. And each of us is responsible for honoring our commitment to excellence, pushing the boundaries and transforming the patient experience, every day.

We all have the power to help, heal and change lives — beginning with our own. That’s the power of the Cleveland Clinic Health System team, and The Power of Every One.

Job Title

Histology Technician/Histotechnologist - Immunohistochemistry

Location

Cleveland

Facility

Cleveland Clinic Main Campus

Department

Immunohistochemistry-Diagnostics Institute

Job Code

C20008

Shift

Evenings

Schedule

4:00pm-12:30am

Job Summary

Job Details

*This position is eligible for a sign-on bonus of $5,000*

Join Cleveland Clinic’s Main Campus where research and surgery are advanced, technology is leading-edge, patient care is world class and caregivers are family. Here, you will work alongside a passionate and dedicated team, receive endless support and appreciation, and build a rewarding career with one of the most respected healthcare organizations in the world.

At Cleveland Clinic, every detail matters when it comes to delivering exceptional patient care—and that starts in the lab. As a Histotechnologist or Histology Technician, you’ll play a vital role behind the scenes, preparing high-quality tissue samples that support accurate diagnoses and life-changing treatment decisions.

In this role, you’ll bring precision, technical expertise, and attention to detail to every specimen, working as part of a collaborative team dedicated to excellence. Your contributions will directly impact patient outcomes, ensuring physicians have the information they need to provide the best possible care.

Join a team that values your skills, supports your growth, and empowers you to make a meaningful difference every day.

We will hire our histology laboratory personnel into one of two job titles based on educational background, certification, and experience:

• Histology Technician
• Histotechnologist

The caregiver in this role works evenings| 4:00pm—12:30am.

Histology Technician Role:

A caregiver who excels in this role will:

• Prepare, process, embed, and section tissue specimens using standard histology equipment, including microtomes and cryostats
• Perform routine and specialized staining procedures, including histochemical and enzyme stains
• Mount, label, and distribute slides for pathologist review
• Maintain laboratory equipment, perform daily maintenance, and coordinate repairs as needed
• Prepare reagents, buffers, and solutions to support testing procedures
• Accurately document patient and specimen data, maintain records, and track lab statistics
• Ensure cleanliness, organization, and quality control of lab instruments and workspaces
• Support training and serve as a resource for students, trainees, and residents

Minimum qualifications for the ideal future caregiver include:

• American Society for Clinical Pathology (ASCP) Certification eligible in the field of Histology

Preferred qualifications for the ideal future caregiver include:

• One year of experience

Histotechnologist Role:

A caregiver who excels in this role will:

• Perform routine and developmental immunochemistry and molecular laboratory techniques.
• Analyze and evaluate assays for sensitivity and specificity.
• Embed and prepare sections for various procedures by cutting off frozen or paraffin embedded tissue.
• Transport tissue specimens to the laboratory.
• Perform immunohistochemical and in-situ hybridization procedures, including handling and storing probes and antibodies.
• Mount, label and distribute prepared microscope slides.
• Prepare reagent buffers, solutions and stains.
• Replace reagents and perform daily maintenance on automated instrumentation.
• File surgical and autopsy blocks used for immunohistochemical techniques.

Minimum qualifications for the ideal future caregiver include:

• Bachelor’s Degree in Biology, Microbiology, Chemistry or a related field or meet the CLIA qualifications for Histotechnologist (HTL)
• Histotechnician (HT) or Histotechnologist (HTL) certification or certification eligible by the American Society for Clinical Pathology (ASCP)
• Working knowledge of OSHA requirements concerning chemical hygiene and bloodborne pathogens

Preferred qualifications for the ideal future caregiver include:

• Hands-on laboratory experience from an accredited Histotechnology school or one year of prior histology laboratory experience

Physical Requirements:

• Requires manual dexterity and visual acuity when handling specimens, slides and utilizing instrumentation.
• Ability to safely handle potentially infectious patient specimens, carcinogenic substances, odorous and other hazardous materials to which they may be exposed.
• Typical physical demands include ability to sit, stand or walk extensively.

Personal Protective Equipment:

• Follows standard precautions using personal protective equipment as required.

The policy of Cleveland Clinic Health System and its system hospitals (Cleveland Clinic Health System) is to provide equal opportunity to all of our caregivers and applicants for employment in our drug free environment. All offers of employment are followed by testing for controlled substances.

Cleveland Clinic Health System administers an influenza prevention program. You will be required to comply with this program, which will include obtaining an influenza vaccination on an annual basis or obtaining an approved exemption.

Decisions concerning employment, transfers and promotions are made upon the basis of the best qualified candidate without regard to color, race, religion, national origin, age, sex, sexual orientation, marital status, ancestry, status as a disabled or Vietnam era veteran or any other characteristic protected by law. Information provided on this application may be shared with any Cleveland Clinic Health System facility.

If applying for a Florida position, please see the following website for more information on the background screening requirements required by the Agency of Health Care Administration: https://info.flclearinghouse.com/

Please review the Equal Employment Opportunity poster.

Cleveland Clinic is pleased to be an equal employment opportunity employer.