Health Informatics & Interoperability Lead (Remote Eligible)

Mathematica; Ann Arbor (MI); On-site; USD 140,000 - 165,000; Full time

Job summary

Mathematica seeks a Health Informatics & Interoperability Lead to guide strategic and technical activities across health data standards, interoperability, and digital quality measurement. You will shape FHIR strategy, oversee architecture, and mentor teams delivering interoperable solutions for federal, state, and other health care initiatives.

The role combines senior leadership with hands-on guidance on data standards, APIs, and EHR integration, collaborating with clients and national

Qualifications

• Master’s degree required in health informatics or related field; doctoral or clinical degree preferred.
• 10+ years in health informatics or related fields.
• Deep expertise in health informatics and interoperability, including guiding strategic, architectural decisions.
• Demonstrated expertise with FHIR and HL7 standards, including APIs and implementation guides.
• Experience designing, implementing, or advising on interoperable health data solutions.

Responsibilities

• Serve as senior health informatics and interoperability SME to internal teams and clients across FHIR, data standards, and interoperability.
• Lead and advance Mathematica’s interoperability strategy including architecture, standards alignment, and capability development.
• Provide technical leadership on projects involving interoperable health data and digital quality measurement (FHIR-based).
• Guide translation and exchange of clinical/administrative data across EHRs and health IT systems.
• Mentor staff, contribute to business development, and represent Mathematica in standards forums.

Skills

Health informatics

Interoperability leadership

FHIR expertise

HL7 standards

Data modeling

Education

Master’s degree in health informatics or related field

Doctoral or clinical degree preferred

Tools

FHIR APIs

CQL/QDM/QRDA

SQL/Python

Job description

About Mathematica

Mathematica applies expertise at the intersection of data, methods, policy, and practice to improve well‑being around the world. We collaborate closely with public‑and private‑sector partners to translate big questions into deep insights that improve programs, refine strategies, and enhance understanding using data science and analytics. Our work yields actionable information to guide decisions in wide‑ranging policy areas, from health, education, early childhood, and family support to nutrition, employment, disability, and international development. Mathematica offers our employees competitive salaries, and a comprehensive benefits package, as well as the advantages of being 100 percent employee owned. As an employee stock owner, you will experience financial benefits of ESOP holdings that have increased in tandem with the company’s growth and financial strength. You will also be part of an independent, employee‑owned firm that is able to define and further our mission, enhance our quality and accountability, and steadily grow our financial strength. Read more about our benefits here: https://www.mathematica.org/career-opportunities/benefits-at-a-glance.

About Mathematica

Mathematica applies expertise at the intersection of data, methods, policy, and practice to improve well‑being around the world. We collaborate closely with public‑and private‑sector partners to translate big questions into deep insights that improve programs, refine strategies, and enhance understanding using data science and analytics. Our work yields actionable information to guide decisions in wide‑ranging policy areas, from health, education, early childhood, and family support to nutrition, employment, disability, and international development. Mathematica offers our employees competitive salaries, and a comprehensive benefits package, as well as the advantages of being 100 percent employee owned. As an employee stock owner, you will experience financial benefits of ESOP holdings that have increased in tandem with the company’s growth and financial strength. You will also be part of an independent, employee‑owned firm that is able to define and further our mission, enhance our quality and accountability, and steadily grow our financial strength. Read more about our benefits here: https://www.mathematica.org/career-opportunities/benefits-at-a-glance.

Primary Duties And Responsibilities

Mathematica seeks a Health Informatics & Interoperability Lead to provide strategic, technical, and subject matter leadership across health information interoperability, health informatics, digital health, clinical quality measurement and improvement, and value‑based care initiatives. This individual will help shape and advance Mathematica’s interoperability and Fast Healthcare Interoperability Resources (FHIR) strategy and capabilities and provide senior‑level guidance to multidisciplinary teams working at the intersection of health policy, clinical data, health information technology, quality measurement, data standards, and technology. The Health Informatics & Interoperability Lead will work across a diverse portfolio of federal, state, and other health care initiatives focused on modernizing health data infrastructure, improving the exchange and use of health information, advancing digital quality measurement, and strengthening data‑driven health care delivery and public health. Clients and partners include agencies within the U.S. Department of Health and Human Services, such as the Centers for Medicare & Medicaid Services (CMS), as well as state health and public health agencies and other organizations across the health care ecosystem. The Health Informatics & Interoperability Lead will bring deep expertise in health information technology standards, interoperability frameworks, clinical and administrative data, terminology and coding, and the exchange and use of health information across systems. This individual will apply technical and strategic knowledge of FHIR, HL7 standards, implementation guides, application programming interfaces (APIs), health information exchange, clinical data models, terminology standards, and related technologies to support interoperable data solutions across a range of health care use cases (including public health). The role will also provide thought leadership and oversight in digital quality measurement and related interoperability applications, including FHIR‑based quality measurement, electronic clinical quality measures, and clinical decision support. The individual will lead and mentor technical staff, contribute to business development and capability building, and represent Mathematica with clients, partners, and national standards and interoperability communities. As a senior leader in a growing area of Mathematica’s portfolio, this individual will help identify and shape new opportunities, strengthen Mathematica’s interoperability capabilities, and will apply interoperability expertise across existing and emerging projects.

This opportunity is available on either a full‑ or part‑time basis.

Core Responsibilities

• Serve as a senior health informatics and interoperability subject matter expert to internal project teams and external clients and stakeholders, providing strategic and technical leadership across FHIR, health data standards, health information exchange, EHR‑enabled solutions, digital quality measurement, interoperable analytics, and possibly clinical decision support.
• Lead and advance Mathematica’s interoperability and FHIR strategy, including strategic planning, technical architecture and approaches, standards alignment, capability development, implementation strategy, and positioning for future client needs.
• Provide technical leadership on projects and initiatives involving interoperable health data and digital quality measurement, including:
  • Electronic clinical quality measures, FHIR‑based measures, and quality reporting
  • FHIR resources, profiles, implementation guides, APIs, terminology standards, data models, and other HL7 standards
  • CQL, QDM, QRDA, value sets, and measure development and implementation tools
• Interoperability implementation, testing, validation, and data quality
• Guide the translation and exchange of clinical, administrative, quality, and other health care data across EHRs, health information systems, data platforms, analytic environments, and other technology ecosystems.
• Guide interoperability implementation, testing, validation, conformance, data quality, terminology mapping, and alignment with applicable standards and implementation guides.
• Translate and synthesize policy, regulatory, clinical, technical, operational, and business requirements into interoperability strategies, technical specifications, implementation guidance, solution designs, analytic approaches, and recommendations for project teams and clients.
• Work with current and prospective clients to understand their strategic goals, workflows, data environments, technology ecosystems, interoperability challenges, and technical needs and develop appropriate approaches and solutions.
• Contribute to business development and growth by identifying emerging client needs and opportunities, developing technical and solution strategies, contributing to proposal and capture activities, and participating in client presentations and discussions.
• Mentor, coach, and provide technical oversight to staff working across health informatics, interoperability, digital quality measurement, clinical data, and related technical projects.
• Represent Mathematica in national meetings, standards development activities, technical expert panels, client forums, HL7 community activities, and other health informatics, interoperability, and quality measurement venues.
• Provide consultation and training internally on interoperability standards and practices, FHIR strategy and implementation, health information exchange, clinical data standards, digital quality measurement, and emerging health informatics practices.

Required Qualifications

• Master’s degree required in health informatics, computer science, data science, public health, health policy, statistics, mathematics, public administration, public policy, or a related field. Doctoral degree or clinical degree preferred.
• At least ten (10) years of experience in health informatics, interoperability, health data standards, health information technology, clinical data, digital quality measurement, analytics, clinical operations, or related fields, or an equivalent combination of education and experience.
• Deep demonstrated experience in health informatics and interoperability, including the ability to guide strategic, architectural, and technical implementation decisions.
• Demonstrated expertise with FHIR and related HL7 standards, including FHIR resources, profiles, implementation guides, APIs, and practical implementation approaches.
• Experience designing, implementing, evaluating, or advising on interoperable health data solutions involving EHRs, health information systems, clinical data repositories, health information exchange, APIs, or related technology environments.
• Strong understanding of health care data models, clinical and administrative data, terminology standards, standardized code systems, value sets, data mapping, and semantic interoperability.
• Demonstrated understanding of health care workflows and how clinical, operational, technical, and policy requirements affect interoperability and health information exchange.
• Experience translating business, policy, clinical, and operational requirements into interoperability architecture, technical specifications, implementation approaches, or solution designs.
• Experience with digital quality measurement and related interoperability use cases, including electronic clinical quality measures, FHIR‑based quality measurement, clinical decision support, or quality reporting.
• Working knowledge of relevant digital quality measurement standards and tools, which may include CQL, QDM, QRDA, MADiE, VSAC, Bonnie, or related authoring and testing environments.
• Technical or programming experience sufficient to provide senior‑level oversight of interoperability and informatics solutions. Relevant experience may include CQL, SQL, Python, R, JavaScript, FHIR APIs, or other software development and analytic environments.
• Familiarity with interoperability implementation and testing approaches, including standards conformance, validation, data quality, terminology mapping, and real‑world implementation challenges.
• Knowledge of federal health IT and interoperability policy, CMS quality and value‑based care programs, health IT certification, health information exchange, and related regulatory environments, with demonstrated ability to interpret and operationalize relevant policies, regulations, standards, and implementation guides.
• Experience participating in HL7, standards development, health informatics, quality measurement, or interoperability communities.
• Experience supporting federal health clients and navigating federal contracting, client engagement, or cross‑contractor environments.
• Demonstrated experience contributing to business development, proposal strategy, capture activities, solution design, capability development, or client relationship development.
• Ability to communicate complex technical concepts to varied audiences and lead multi‑stakeholder technical discussions, architecture and design sessions, client meetings, and standards‑focused forums.
• Demonstrated ability to lead multidisciplinary teams, delegate effectively, provide constructive feedback, develop staff, and manage multiple priorities under deadlines.

Additional Preferred Experience

• Clinical background or clinical training, such as nursing, medicine, pharmacy, allied health, clinical informatics, health information management, or related clinical experience.
• Experience developing, implementing, or contributing to FHIR implementation guides, profiles, extensions, or other interoperability specifications.
• Experience working with EHR platforms and vendor implementations
• Operational experience in health care organizations, including quality improvement, patient safety, care management,
• EHR optimization, clinical analytics, population health, or value‑based care.
• Experience configuring, optimizing, implementing, or using EHRs, clinical data repositories, registries, health information exchanges, or other clinical information systems.
• Relevant certifications or professional credentials in clinical informatics, health information management, health information technology, interoperability, or related disciplines.

Compensation Details

This position offers an anticipated base salary range of $140,000 - $165,000 annually. This position is eligible for an annual bonus opportunity based on individual and company performance.

Candidates whose experience exceeds the stated qualifications are also encouraged to apply. As ongoing needs/opportunities are evaluated, the hiring team may consider expanding the scope and level of the role.

We are an Equal Opportunity Employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity, status as a veteran, and basis of disability or any other federal, state or local protected class.

At Mathematica, we understand the importance of building relationships with colleagues. If you’re not located near one of our offices but would like opportunities to meet up with co‑workers, we offer coworking spaces where available. Ask your Talent Acquisition partner for more information about this opportunity and whether it’s an option in your area.

Any offer of employment will be contingent upon passing a background check. Various federal agencies with whom we contract require that staff successfully undergo security clearance as a condition of working on the project. If you are assigned to such a project, you will be required to obtain the requisite security clearance. Additionally, if you participate in/complete the application process and are denied, Mathematica may choose to terminate your employment.

We take pride in our employees and in their commitment to excellence. We encourage staff to collaborate in developing creative solutions to difficult problems and to share the responsibility and enjoyment of carrying out complex projects. This collegial spirit has helped us earn our reputation for innovative and high quality work.