Head of Pharmacovigilance

Ladders; United States; Remote; USD 378,000 - 420,000; Full time

Benefits offered by this job

Medical/dental/vision premiums covered

Company-paid life insurance and AD&D

401(k) matching up to 6%

Job summary

Ladders is seeking a Head of Pharmacovigilance to lead the safety oversight across the organization, spanning clinical development and commercial products. This remote role focuses on shaping the safety operating model, partnering with cross-functional teams, and providing senior medical judgement on benefit-risk decisions within a highly regulated environment.

The role emphasizes strengthening safety systems, reporting, and interactions with regulatory authorities, while driving quality and

Qualifications

• Physician with extensive pharmacovigilance experience across clinical development and commercial settings.
• Proven ability to lead safety strategy and governance.
• Experience chairing safety governance bodies and interacting with health authorities.

Responsibilities

• Lead and oversee the entire pharmacovigilance function, ensuring compliance and quality across all products.
• Directly manage postmarketing safety surveillance and reporting for commercial products.
• Supervise clinical development safety through the PV Clinical Development Lead, retaining final authority on safety decisions.
• Design and implement the pharmacovigilance operating model, collaborating with cross-functional teams.
• Establish and maintain the pharmacovigilance quality system, including SOPs and compliance metrics.

Skills

Pharmacovigilance leadership

Safety governance

IND safety reporting

ICH guidelines

AI in regulated processes

Education

MD/DO or non-US equivalent

Job description

For our client, we are seeking a Head of Pharmacovigilance to join the team of a leader in the Pharmaceuticals & Biotech space.

This role will lead the pharmacovigilance function across the organization, with accountability for safety oversight, quality, and compliance across both clinical development and commercial products. You will shape the safety operating model, partner closely with cross-functional teams, and provide senior medical judgement on benefit-risk decisions and governance. The position also carries responsibility for strengthening safety systems, reporting, and regulatory interactions in a highly regulated environment.

Location: Remote

Compensation: $378,000 – $420,000 annually

Responsibilities

• Lead and oversee the entire pharmacovigilance function, ensuring compliance and quality across all products
• Directly manage postmarketing safety surveillance and reporting for commercial products
• Supervise clinical development safety through the PV Clinical Development Lead, retaining final authority on safety decisions
• Design and implement the pharmacovigilance operating model, collaborating with cross-functional teams
• Establish and maintain the pharmacovigilance quality system, including SOPs and compliance metrics

Qualifications

• Physician (MD, DO, or non-US equivalent) with a minimum of twelve years in pharmacovigilance
• Proven experience in building and leading a pharmacovigilance department across clinical and commercial settings
• Demonstrated ownership of safety strategy and senior medical judgment in benefit-risk determinations
• Experience chairing safety governance bodies and interacting with health authorities on safety matters
• Direct knowledge of IND safety reporting and ICH guidelines, with comfort in AI applications in regulated processes

Benefits

• 99% of medical, dental, and vision premiums covered
• Company-paid life insurance, AD&D, and disability benefits
• 401(k) matching up to 6% and long-term stock incentives
• Discretionary quarterly bonuses and flexible wellness benefits
• Generous PTO, paid holidays, and company-wide shutdowns

Our client is an equal opportunity employer. We encourage you to apply even if you don’t meet every qualification—your background could be exactly what this team needs.