GMP Lab Tech II-3

MUSC Health; Charleston (SC); On-site; USD 85,000 - 120,000; Full time

Job summary

The GMP Lab Tech II at MUSC Health performs advanced cellular therapy manufacturing and lab operations within a strict cGMP environment, handling isolation, expansion, enrichment, and cryopreservation of human-derived cellular products for clinical care and development.

You will work in aseptic processing, maintain batch documentation, ensure traceability, and collaborate with clinical, laboratory, research, and quality teams to optimize processes and ensure compliant delivery of next-generation

Qualifications

• Four-year degree in medical technology or biological sciences.
• 2+ years clinical cell therapy experience.
• Basic hematology knowledge.
• Motivation to learn new scientific theory and applications.
• Strong trouble-shooting capabilities.
• Scientific writing skills.

Responsibilities

• Perform complex cellular processing workflows: isolation, expansion, enrichment, selection, culture, cryopreservation and quality control testing.
• Execute aseptic processing within classified cleanroom environments and maintain accurate batch documentation.
• Ensure product traceability, compliance, and quality throughout the manufacturing lifecycle.
• Collaborate with clinical, laboratory, research, and quality teams to develop, validate, and implement novel cellular therapy processes.
• Support process improvement initiatives and SOP development to translate research into clinical applications.

Skills

Clinical cell therapy experience

Attention to detail

Color vision

Scientific writing

Team collaboration

Education

Four-year college degree in medical technology or biological sciences

Master’s degree in medical sciences or related field (preferred)

Tools

Flow cytometry

LIS knowledge (Bluecord/Stemsoft)

Job description

Job Summary

The GMP Lab Tech II performs advanced cellular therapy manufacturing and laboratory operations supporting clinical, translational, and investigational cell therapy programs within a highly regulated GMP environment. This role is responsible for executing complex cellular processing workflows, including cell isolation, expansion, enrichment, selection, culture, cryopreservation, and quality control testing of human‑derived cellular products used in clinical care and therapeutic development. The technician supports end‑to‑end manufacturing operations for advanced cellular therapies by performing aseptic processing activities within classified cleanroom environments, maintaining accurate batch documentation, and ensuring product traceability, compliance, and quality throughout the manufacturing lifecycle. The role applies specialized technical expertise in the processing of apheresis‑derived products, immune cell populations, stem cell products, and emerging cellular therapies while adhering to established cGMP, cGTP, biosafety, and contamination control requirements. In collaboration with clinical, laboratory, research, and quality teams, the GMP Lab Tech II supports the development, optimization, validation, and implementation of novel cellular therapy manufacturing processes, including CAR‑T, mesenchymal stem cell, dendritic cell, and other advanced therapeutic platforms. The technician contributes to process improvement initiatives, equipment and procedure qualification activities, SOP development, and implementation of standardized workflows that enable the translation of innovative cellular therapies from research environments into clinical application. The GMP Lab Tech II performs complex immunological, hematological, and cellular analyses to support product characterization, assay validation, and laboratory quality programs. Through advanced laboratory techniques including flow cytometry, ELISA‑based assays, functional immune testing, and cellular analysis, this role evaluates product performance, investigates technical challenges, and generates data to support manufacturing decisions and continuous improvement. The GMP Lab Tech II serves as a critical technical contributor within the cellular therapy program, bridging laboratory expertise, manufacturing execution, and quality oversight to support the safe, reliable, and compliant delivery of next‑generation cellular therapies.

Education and Work Experience

• Four‑year college degree with major in medical technology or biological sciences
• 2+ years clinical cell therapy experience
• Basic hematology knowledge
• Motivation and initiative to learn new scientific theory and applications
• Mature judgment
• Work independently with regular review of progress and results
• Proven team player
• Collaborate and communicate effectively across functions
• Interpret data thoroughly
• Strong trouble‑shooting capabilities
• Scientific writing skills, including preparation of clear, concise SOPs and technical reports
• Strong math skills
• Attention to detail
• Must be able to differentiate between colors and pass a standardized color vision screen to perform this role

Preferred Qualifications

• Master’s college degree with a major in medical sciences or related field
• Experience working within an academic cGMP laboratory, including familiarity with FDA and FACT accreditation requirements
• Flow cytometry expertise
• Immunotherapy experience
• Cell selection operation experience (e.g., manual or CliniMACs)
• Moderate LIS knowledge (e.g., Bluecord, Stemsoft)
• A strong understanding of cGMP/cGTP standards

Physical Requirements

Continuous: 6‑8 hours per shift; Frequent: 2‑6 hours per shift; Infrequent: 0‑2 hours per shift. Ability to perform job functions while standing, sitting, walking, climbing stairs, working indoors and outdoors in temperature extremes, from elevated areas, in confined spaces, and at kneeling positions. Ability to bend, twist, squat, and perform gross motor activities. Ability to grasp, manipulate, and pinching. Ability to lift and carry 50 lbs. unassisted, and lift/lower objects 50 lbs. from the floor. Ability to reach overhead, all directions, handle 25‑lb loads from 36” to overhead, and exert up to 50 lbs. of force. Ability to maintain vision 20/40 corrected, discriminate colors, determine depth perception, and maintain hearing acuity. Ability to work rotating shifts, overtime as required, and in a latex‑safe environment. Must pass a respirator fit test.

EEO Statement

The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need. Medical University of South Carolina participates in the federal E‑Verify program to confirm the identity and employment authorization of all newly hired employees.