Global VP, Drug Safety & Pharmacovigilance

Deciphera Pharmaceuticals; Waltham (MA); On-site; USD 335,000 - 460,000; Full time

Benefits offered by this job

Annual bonus

Benefits package

Parental leave

Growth opportunities

Job summary

Deciphera Pharmaceuticals is seeking a strategic Vice President, Pharmacovigilance to lead our global drug safety function. You will set safety governance, oversee risk management, signal detection, and regulatory safety support across investigational and marketed products.

You will build a high‑performing team and collaborate with Clinical Development, Regulatory Affairs, Medical Affairs, and Quality to ensure inspection readiness and continuous safety improvements across a growing portfolio.

Qualifications

• MD, DO, PharmD, PhD, or equivalent advanced scientific or healthcare degree.
• 15+ years of progressive experience in pharmacovigilance, clinical safety, drug safety, or drug development within the biotechnology or pharmaceutical industry.
• 8+ years of leadership experience managing global pharmacovigilance, clinical safety, or patient safety organizations.
• Demonstrated experience supporting products across clinical development and commercialization.
• Deep understanding of global pharmacovigilance regulations, guidelines, and industry best practices, including FDA, EMA, ICH, GCP, and other applicable requirements.
• Experience with safety governance, benefit-risk assessment, signal detection, risk management, safety reporting, and inspection readiness.
• Track record of successful health authority interactions, regulatory inspections, audits, and cross-functional safety leadership.
• Strong strategic leadership, communication, decision-making, and stakeholder management skills.

Responsibilities

• Develop and execute the global pharmacovigilance strategy in alignment with corporate objectives, regulatory requirements, and Deciphera's commitment to patient safety.
• Provide executive leadership for benefit-risk evaluation, safety governance, safety surveillance, signal management, and risk management across investigational and marketed products.
• Serve as a senior safety advisor to executive leadership and represent Pharmacovigilance in governance committees, leadership forums, and interactions with health authorities.
• Ensure global pharmacovigilance activities are compliant, inspection-ready, scientifically rigorous, and aligned with applicable regulatory requirements, GCP standards, and internal quality systems.
• Establish and evolve scalable pharmacovigilance systems, processes, quality frameworks, vendor partnerships, and operational capabilities to support a growing global portfolio.
• Build, develop, and lead a high-performing pharmacovigilance organization while fostering a culture of scientific excellence, accountability, collaboration, and patient-focused decision making.

Skills

Strategic leadership

Regulatory compliance

Pharmacovigilance leadership

Stakeholder management

Communication

Global safety strategy

Risk management

Signal detection

Leadership communication

Education

MD/DO/PharmD/PhD or equivalent

Job description

Deciphera Pharmaceuticals is seeking a strategic Vice President, Pharmacovigilance to lead our global drug safety function. You will set safety governance, oversee risk management, signal detection, and regulatory safety support across investigational and marketed products.

You will build a high‑performing team and collaborate with Clinical Development, Regulatory Affairs, Medical Affairs, and Quality to ensure inspection readiness and continuous safety improvements across a growing portfolio.