Global Senior Director, Nonclinical Toxicology

Bausch + Lomb; Montpelier (VT); On-site; USD 225,000 - 300,000; Full time

Benefits offered by this job

Medical insurance

Dental insurance

Vision insurance

401(k) plan with company match

Tuition reimbursement

Job summary

Bausch + Lomb is seeking a Senior Director, Pharma Toxicology to lead nonclinical safety across its pharma, OTC, and consumer portfolio. You will set global toxicology strategy, build the organization, and serve as the senior scientific authority on toxicology for development programs and regulatory interactions.

Reporting to R&D leadership, you will partner with regulatory, clinical, quality, and commercial teams to accelerate development, ensure GLP compliance, and oversee CROs.

Qualifications

• Ph.D. in Toxicology or related discipline.
• 15+ years of relevant pharmaceutical industry experience in nonclinical safety/toxicology.
• People leadership experience, including leading managers and building or scaling teams.
• Demonstrated track record of setting nonclinical strategy for multiple programs from discovery through registration and lifecycle management, including direct interaction with the FDA and/or other global health authorities.
• Deep knowledge of global nonclinical regulatory requirements and guidance (e.g., ICH) and GLP regulations.
• Experience managing departmental budgets and strategic CRO/vendor relationships.
• Proven ability to influence senior leadership and communicate complex scientific risk clearly to executive and non-technical audiences.
• Experience in ophthalmology drug development is highly desirable.
• DABT preferred.

Responsibilities

• Define and own the global nonclinical safety and toxicology strategy for pharmaceuticals, over-the-counter products, and consumer goods, aligned with the R&D portfolio and corporate objectives.
• Act as the company's senior subject matter expert in toxicology, representing Bausch + Lomb in meetings with the FDA and other global health authorities and leading nonclinical strategy for key regulatory milestones (e.g., pre-IND, IND, end-of-phase, NDA/MAA, and post-approval).
• Lead nonclinical due diligence for in-licensing, acquisition, and partnership opportunities, and advise senior leadership on nonclinical risks and integration requirements.
• Anticipate evolving regulatory guidance, scientific advances, and industry standards (including New Approach Methodologies and alternatives to animal testing); assess portfolio-wide impact and drive adoption where appropriate.
• Oversee the design, execution, interpretation, and communication of nonclinical safety programs to enable clinical development, regulatory submissions/registrations, product launch, ongoing market support, and compliance activities.
• Provide final scientific review and approval of nonclinical sections of regulatory submissions, safety assessments, and technical reports; ensure scientific rigor and consistency across the portfolio.
• Partner with executive and cross-functional leaders including Product Development, Clinical Development, Analytical Chemistry, Regulatory Affairs, Quality, Compliance, and Commercial to align nonclinical plans with program and business objectives.
• Direct collaboration with international company sites to address nonclinical safety requirements for country-specific submissions, registrations, and ongoing business needs.
• Lead the development, implementation, and continuous improvement of global departmental processes, standards, and best practices, and drive harmonization across sites.
• Represent Bausch + Lomb externally through scientific publications, conference presentations, and industry consortia, enhancing the company's scientific reputation.

Job description

Bausch + Lomb is seeking a Senior Director, Pharma Toxicology to lead nonclinical safety across its pharma, OTC, and consumer portfolio. You will set global toxicology strategy, build the organization, and serve as the senior scientific authority on toxicology for development programs and regulatory interactions.

Reporting to R&D leadership, you will partner with regulatory, clinical, quality, and commercial teams to accelerate development, ensure GLP compliance, and oversee CROs.