Global Head, AI-Driven Clinical Pharmacology & Pharmacometrics

Recursion; New York (NY); Remote; USD 322,000 - 443,000; Full time

Job summary

Recursion, a clinical-stage TechBio company, seeks a visionary VP of Clinical Pharmacology & Pharmacometrics to define enterprise strategy across pharmacology, modeling, and translational science from first-in-human planning to registrational development. Lead a multidisciplinary team and collaborate with FDA/authorities to accelerate dosage decisions and labeling strategies.

You will shape AI-enabled pharmacology workflows, oversee cross-functional programs, and represent Recursion in

Qualifications

• Advanced degree in clinical pharmacology, pharmacometrics, pharmaceutical sciences, quantitative pharmacology, biomedical engineering, medicine, pharmacy, or a related field; PhD, PharmD, or MD preferred
• 15+ years of biotech or pharmaceutical industry experience, including leadership in Clinical Pharmacology, Pharmacometrics, Quantitative Pharmacology, or model-informed drug development
• Proven success leading clinical pharmacology strategy across multiple programs, from FIH to registrational development, submission and labeling
• Deep expertise in PK, PK/PD, exposure–response, exposure–safety, population PK, PBPK, QSP, dose optimization, and model-based trial design
• Experience designing, interpreting, and defending clinical pharmacology studies for global development and regulatory submissions
• Strong understanding of FDA/EMA/MHRA/PMDA/ICH expectations for clinical pharmacology and regulatory documentation
• Demonstrated ability to build and lead high-performing teams and communicate complex quantitative concepts to executives and regulators

Responsibilities

• Set enterprise strategy for Clinical Pharmacology, Pharmacometrics, Translational Modeling, and preclinical-to-clinical data integration
• Own dose strategy from FIH through registrational development and label justification
• Lead quantitative development approaches including population PK, PK/PD, exposure–response, PBPK, QSP and trial simulations
• Design and oversee clinical pharmacology studies including DDI, organ impairment, QT safety, bioavailability, ADME, and special populations
• Partner cross-functionally to inform development strategy and decision-making
• Represent clinical pharmacology in regulatory interactions and ensure high-quality contributions to submissions and labeling
• Build, mentor, and scale a high-performing Clinical Pharmacology and Pharmacometrics function
• Advance AI, automation, and analytics to improve evidence integration and decision making

Skills

Clinical Pharmacology

Pharmacometrics

Model-informed Drug Development

Dose Strategy

Regulatory Strategy

Cross-functional Leadership

AI in Pharmacology

Education

Advanced degree in clinical pharmacology

PhD/PharmD/MD preferred

Tools

Population PK

PK/PD

PBPK

QSP

Exposure-Response Modeling

Clinical Trial Simulations

Job description

Recursion, a clinical-stage TechBio company, seeks a visionary VP of Clinical Pharmacology & Pharmacometrics to define enterprise strategy across pharmacology, modeling, and translational science from first-in-human planning to registrational development. Lead a multidisciplinary team and collaborate with FDA/authorities to accelerate dosage decisions and labeling strategies.

You will shape AI-enabled pharmacology workflows, oversee cross-functional programs, and represent Recursion in