Global Clinical Head (Pulmonologist)- Executive Director

AstraZeneca GmbH; Gaithersburg (MD); Hybrid; USD 332,000 - 498,000; Full time

Benefits offered by this job

401(k) retirement plan

Paid vacation and holidays

Health benefits (medical, dental, etc)

Job summary

AstraZeneca is seeking a Global Clinical Head (Executive Director) to steer clinical development for Infectious Disease products and to lead a cross-functional team toward timely, high-quality medical deliverables. The role involves regulatory interactions and strategic direction across global programs.

The successful candidate will guide Clinical Development Plans, coordinate pivotal Phase 3 studies, and mentor physicians and scientists, while fostering collaboration and integrity across the

Qualifications

• MD degree with board-certification in pulmonology.
• Extensive clinical research in COPD and bronchiectasis.
• 10+ years of pharma industry clinical drug development.
• Experience in early and late-stage program development and trial conduct.

Responsibilities

• Provide global clinical leadership of one or more Infectious Disease products.
• Develop clinical development plans and regulatory documentation (TPP, CDP, NDA/BLA).
• Lead Clinical Project Team to ensure timely, high-quality medical content.
• Represent the team on the Global Project Team overseeing strategy for Infectious Disease products.

Skills

MD degree with pulmonology board

Clinical research in pulmonology

Pharma clinical drug development

Global Phase 3 program leadership

Clinical Development Plans

Regulatory submissions (NDA/BLA)

Matrix leadership

Mentoring physicians/scientists

Cross-functional collaboration

AI/digital mindset in clinical dev

Education

MD degree with board-certification in pulmonology

Job description

Are you a clinical research expert ready for new opportunities? Would you like to play a pivotal role in the development of potential medicines? If you are passionate about being a medical leader for a cross‑functional team in a group that drives action towards the improvement of global public health– join us! As Global Clinical Head(Executive Director)you will have a unique opportunity to further elevate theInfectious DiseaseUnit in one of the world’s most respected biopharmaceutical companies. The role holds a significant development opportunity for the successful candidate whilst contributing to the positive journey that AstraZeneca is on.

Accountabilities:

The Global Clinical Head (GCH) will have overall clinical leadership of one or more globalproducts in the Infectious Disease pipeline specifically related to the prevention of infections in patients with chronic respiratory diseases. The GCH is also responsible for medical/scientific strategies for the clinical components of the Target Product Profile (TPP), Clinical Development Plan (CDP), and regulatory documents(e.g., briefing documents, CTD/BLA, core labelling texts).Within the Clinical Project Team, the GCH has accountability for the clinical, scientific, and value content and delivery of the medical components for the program to time and quality. The GCH will be the team’s voice and representative on the Global Project Team that oversees the overall strategy of Infectious Disease Unit’s products.

Essential Skills/Experience:

• Graduate of a recognized school of medicine with an MD degree or equivalent with board‑certification in pulmonology
• Demonstratedclinical researchexpertise in Pulmonology (especially in COPD and bronchiectasis)
• Pharma industry experience in clinical drug development for at least10years
• Experience in early and late stage program development and trial conduct
• Developed/delivered in parallel multiple complex and/or large studies (e.g., including but not limited to global, pivotal Phase 3 efficacy studies)
• Demonstrated ability to lead the development of a program strategy (e.g., Clinical Development Plans) and be accountable for project plans, timelines, progress, and outcomes
• Writing and delivery of global regulatory submissions(e.g., NDA/BLA submissions, benefit/risk assessment) and interacting with major Health Authorities(e.g., FDA, EMA, PMDA, CDE)
• Demonstrated ability leading and motivating teams in a matrix environment
• Demonstrated ability to lead, coach, and mentor physicians and other clinical scientists
• Significant hands‑on clinical drug development experience and scientific credibility
• Demonstrated ability to cultivate excellent cross‑functional collaborations
• Demonstrated ability to effectively communicate at multiple levels of the organization
• Must demonstrate high integrity
• Organize and deliver Advisory Boards with international Key Opinion Leaders (KOLs)
• Demonstrated AI/digital mindset and experience applying AI‑enabled and generative AI tools to support clinical development activities(e.g., data analysis, medical writing, clinical trial operational efficiency)

Desirable Skills/Experience:

• Infectious disease and/or vaccine expertise
• Named Investigator on a number of clinical trials
• Significant and consistent peer‑reviewed publication track record

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life‑changing medicines. In‑person working gives us the platform we need to connect, work at pace and challenge perceptions.That’s why we work, on average, a minimum of three days per week from the office. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

Why AstraZeneca?

We are a changemaker on the world stage at an exciting frontier of medicine. This is backed by deep knowledge and experience in our field. Building on this, we lead the way into the future with energy and drive. We are helping to transform healthcare and build pandemic preparedness to protect against future health crises and to bring lasting immunity to people around the globe. We are committed to our central role in addressing pandemic and endemic diseases and ensuring our products continue to reach and benefit millions of people around the world.

The annual base salary for this position ranges from USD 331,873.60 – 497,810.40. However, base pay offered may vary depending on multiple individualized factors, including market location, job‑related knowledge, skills, and experience. In addition, our positions offer a short‑term incentive bonus opportunity; eligibility to participate in our equity‑based long‑term incentive program (salaried roles) or to receive a retirement contribution (hourly roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at‑will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Date Posted

19-Aug-2026

Closing Date

03-Sep-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.