Global Clinical Development Medical Director

Regulatory Toolkit; Gaithersburg (MD); On-site; USD 250,000 - 375,000; Full time

Benefits offered by this job

401(k) plan

Health benefits

Paid vacation and holidays

Job summary

AstraZeneca is seeking a Global Clinical Development Medical Director to lead medical strategy for infectious disease programs. You will guide cross-functional teams, oversee trial design and safety oversight, and interact with regulatory authorities.

The role emphasizes AI-enabled tools, high integrity, and office-based work at AstraZeneca sites, with a strong emphasis on translational medicine and publications.

Qualifications

• Fully qualified physician with MD or MD-PhD.
• Experience in clinical drug development and pharma setting preferred.
• Strong English communication, written and spoken.

Responsibilities

• Provide medical and scientific leadership in global development of infectious disease medicines.
• Design, execute, and interpret Phase 1–3 trials.
• Build relationships with external investigators and key opinion leaders.
• Collaborate with Safety, Biostatistics, Regulatory, Clinical Operations and Translational Medicine.
• Oversee safety reviews and regulatory writing for submissions.

Skills

Pulmonology

Infectious disease

Clinical development

Clinical trials design

Regulatory writing

Teamwork

English communication

Education

MD or MD PhD

Job description

Global Clinical Development Medical Director

Are you a clinical research physician ready for new opportunities? Would you like to play a pivotal role in the development of potential medicines? If you are passionate about being a medical leader for a cross-functional team in a group that drives action towards the improvement of global public health– join us! As a Global Clinical Development Medical Director you will have a unique opportunity to further elevate the Infectious Disease unit in one of the world’s most respected biopharmaceutical companies. The role holds a great development opportunity for the successful candidate whilst contributing to the positive journey that AstraZeneca is on.

Accountabilities

• Providing medical and scientific leadership in the global development of new medicines targeted at indications in the field of infectious diseases
• Help design, execute, and interpret clinical trials in one or more development programs (Phase 1 through Phase 3)
• Build strong relationships with a network of external scientific specialists and opinion leaders as well as site investigators
• Work closely with colleagues in other internal functions including Patient Safety, Biometrics, Regulatory Affairs, Clinical Operations, and Translational Medicine
• Medical oversight to ensure the safety of study participants including review of Adverse Events of Special Interest and Serious Adverse Events and review and writing of safety narrative reports
• Medical oversight responsibilities for medical activities outsourced to third party vendors
• Provide expert medical input and writing of regulatory documents and interactions/responses with regulatory authorities
• Provide expert medical and scientific analysis and interpretation of data from ongoing studies and in the literature
• Prepare publications and presentations for scientific meetings and congresses

Essential Skills/Experience

• Fully qualified physician (MD or MD PhD) with clinical experience in pulmonology (preferred), infectious disease, or other relevant specialty
• 1-3 years of experience in clinical drug development, preferably from pharma industry
• Strong understanding of clinical trials methodology with experience in the design, execution, and interpretation of clinical studies (e.g., medical monitoring, data cleaning, clinical study report writing)
• Excellent teamwork and cross-functional collaboration skills
• Ability to communicate effectively in clinical team settings
• Excellent verbal and written communication skills (including giving presentations) in English
• Demonstrated AI/digital mindset and experience applying AI-enabled and generative AI tools to support clinical development activities (e.g., data analysis, medical writing, clinical trial operational efficiency)
• Must demonstrate high integrity
• Be office based at an AstraZeneca site at least 3 days a week

Desirable Skills/Experience

• Additional clinical experience in vaccines and/or monoclonal antibodies
• Named Investigator on several clinical trials
• 1-3 years of pharmaceutical industry knowledge and experience
• Progressed medicines into first time in human Phase 1, Phase 2 delivery of proof of principle, and Phase 3 pivotal efficacy studies
• Experience with Translational programs moving from preclinical to first in human studies and interpretation of immunological assay results
• Significant and consistent peer-reviewed publication track record

The annual base pay for this position ranges from $249,827.20 - $374,740.80. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility toparticipatein our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coveragein accordance withthe terms and conditions of the applicable plans.Additionaldetails of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Date Posted

27-Oct-2026

Closing Date

09-Nov-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.