General Supervisor, Prenatal

BillionToOne; Union City (CA); On-site; USD 192,932 - 218,657; Full time

Benefits offered by this job

Open, transparent culture with weekly Town Hall meetings

Extremely generous Family Bonding Leave

Daily on-site lunches from top eateries

State-of-the-art gym

Job summary

BillionToOne in Union City, California is seeking a driven General Supervisor to lead their growing CLIA team. This role focuses on overseeing prenatal testing labs and ensuring compliance with high complexity operational standards.

Qualified candidates will hold a California Clinical Laboratory Scientist License and have 4-5 years of laboratory supervisor experience, driving improvements and fostering a collaborative environment. The position offers a comprehensive benefits package, including extensive family leave, medical benefits, and professional growth opportunities.

Qualifications

• Current or previous supervisory experience that includes direct supervision of lab staff.
• Minimum of 4-5 years of CLS experience in a clinical setting.
• A current California Clinical Laboratory Scientist License.

Responsibilities

• Lead clinical laboratory daily supervision in alignment with company values.
• Oversee day-to-day operations including scheduling and troubleshooting.
• Manage CLIA direct reports and facilitate communication between teams.

Skills

Leadership

Communication

Attention to Detail

Team Collaboration

Education

Bachelor's degree in chemical, physical or biological sciences

Tools

Google Docs

LIMS systems

Next-Generation Sequencing

Job description

A Rare Opportunity to Shape the Future of Genomics

Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on our mission to make life‑changing diagnostics accessible to all. We don't just aim for incremental improvements; we build products that are 10x better than anything that exists today. Our scientists, engineers, sales executives, and visionaries are united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting‑edge science meets human compassion, and every innovation you contribute helps remove the fear of the unknown from some of life's most critical medical moments. If you're driven by purpose, energized by innovation, and ready to help shape the future of precision medicine at scale, this is where you belong.

General Supervisor (with California Clinical Laboratory Scientist License)

We are looking for a driven General Supervisor to support UNITY, the only non‑invasive prenatal test (NIPT) that can detect inherited disorders such as sickle cell disease, spinal muscular atrophy, and cystic fibrosis in the baby directly from maternal blood. These disorders are extremely severe, but early detection and intervention can significantly improve outcomes. You will lead and oversee our growing superstar CLIA team responsible for pregnancy blood sample processing in a high complexity, high‑growth CLIA setting. The General Supervisor is an onsite position and reports to the Director of Laboratory Operations.

Shift Hours

• Mon-Fri PM
• Weekday PM, 20% differential

Responsibilities

• Lead clinical laboratory daily supervision in alignment with company values and mission
• Hold General Supervisor delegation and responsibilities including oversight and support of day‑to‑day operations (Pre‑analytical and Analytical), scheduling, and troubleshooting
• Manage CLIA direct reports including licensed and/or unlicensed staff (CLS, Clinical Laboratory Assistants)
• Oversee continuous process improvement projects including reagent quality control, tech transfer, troubleshooting, training, and validations
• Facilitate communication between laboratory teams and other departments or stakeholders
• Participate in recruiting efforts and hiring to meet sample volume demands
• Foster a collaborative team environment for continuous growth and building skillsets
• Partial owner of and leading execution of company objectives and key results

Requirements

• Bachelor's degree in chemical, physical or biological sciences
• Current or previous supervisory experience that includes direct supervision of lab staff
• Minimum of 4-5 years of CLS experience in a clinical setting (molecular and/or high‑complexity laboratory experience preferred)
• A current California Clinical Laboratory Scientist License that meets requirements for Testing Personnel under CLIA regulations (42 CFR Part 493) (ASCP, CGMBS or generalist license is required)
• Hands‑on training and experience with manual molecular biology protocols, including DNA extraction, PCR, and automated liquid handlers
• Advanced knowledge of Google Docs, Word, Excel, basic statistics and familiarity with LIMS systems and Next‑Generation Sequencing
• Excellent leadership, communication, and interpersonal skills
• Strong attention to detail and ability to work flexibly and well under given timeframes
• Self‑starter and dynamic team player with excellent verbal and written skills

Nice‑To‑Haves

• Previous CLIA General Supervisor experience
• Start‑up experience
• Knowledge of medical genetics
• Experience in a cell‑free DNA setting

Benefits and Perks

• Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
• Open, transparent culture that includes weekly Town Hall meetings
• The ability to indirectly or directly change the lives of hundreds of thousands patients
• Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
• Extremely generous Family Bonding Leave for eligible employees (16 weeks, paid at 100%)
• Supplemental fertility benefits coverage
• Retirement savings program including a 4% Company match
• Increase paid time off with increased tenure
• Latest and greatest hardware (laptop, lab equipment, facilities)
• Daily on‑site lunches provided from top eateries
• A variety of perks on campus (state‑of‑the‑art gym, restaurant)
• Free on‑site EV charging (compatible with all EVs, including Tesla)

Compensation: We offer a total compensation package of $263,772 per year, including a base pay range (inclusive of shift differential) of $192,932 - $218,657 per year.

BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.