Functional Genomics Senior Scientist/Assistant Director

Ionis Brand; Carlsbad (CA); Hybrid; USD 138,000 - 211,000; Full time

Benefits offered by this job

Ionis Benefits

Full Benefits Link available

Job summary

Ionis Pharmaceuticals, Inc. seeks a highly skilled Senior Scientist / Assistant Director in Functional Genomics, either remote or hybrid in Carlsbad, CA. The role combines strategic research leadership with hands-on omics data analysis to advance novel therapeutics.

The successful candidate will have a Ph.D., strong publications, and expertise in single-cell omics, network inference, and ML, plus Linux, Python/R, and cloud familiarity. Excellent communication and collaboration are essential.

Qualifications

• Ph.D. in Computational Biology or related field with post-PhD experience.
• Strong track record of publications and presentations.
• Experience with omics analysis, network inference, and machine learning.
• Proficiency with Python or R and Linux; AWS familiarity is a plus.
• Excellent oral and written communication; ability to work in a fast-paced environment.

Responsibilities

• Collaborate with R&D across disease areas to analyze omics data and identify targets.
• Guide study design for omics-based experiments with input to experimental groups.
• Integrate data from transcriptome, proteome, sequencing, and other sources.
• Communicate findings to diverse scientific audiences in cross-disciplinary teams.
• Generalize and document data integration pipelines and analysis strategies.

Skills

Communication skills

Team collaboration

Fast-paced work environment

Education

Ph.D. in Computational Biology or related field

Tools

Linux

Git

Python

R

Jupyter

RStudio

VSCode

AWS

Job description

Headquartered in Carlsbad, California, and with offices in Boston, Massachusetts, and Dublin, Ireland, Ionis has been at work for more than three decades discovering medical breakthroughs that have redefined life for people with serious diseases. We’re pioneers in RNA-targeted medicines, and our platform continues to revolutionize drug discovery and transform lives for patients with unmet needs. With multiple marketed medicines and a leading pipeline in neurology, cardiology and select areas of high patient needs, we continue to drive innovation in RNA therapies in addition to advancing new approaches in gene editing to provide greater value to patients and are well positioned financially to deliver on our strategic goals.

At Ionis, we pride ourselves on cultivating a challenging, motivating and rewarding environment that fosters innovation and scientific excellence. We know that our success is a direct result of the exceptional talents and dedication of our employees.

With an unprecedented opportunity to change the course of human health, we look to add diverse individuals, skill sets and perspectives to our exceptional team. We continue to invest time, money and energy into making our onsite, hybrid and remote work environments a place where solid and lasting relationships are built and where our culture and employees can thrive.

Functional Genomics Senior Scientist/Assistant Director

Remote or Carlsbad, CA (Hybrid)

SUMMARY:

We are currently seeking a highly motivated individual for the position of Senior Scientist / Assistant Director in our Functional Genomics group. This posting will be leveled as Senior Scientist or Assistant Director based on candidate’s experience and interview performance. A successful candidate will be a strategic member of a fast-paced and interactive research team contributing to the discovery of novel therapeutics. Well-suited candidates will have a systems level approach to understanding biology that harmonizes multiple interacting functional inputs including transcriptional regulation, protein function and larger order (cellular and tissue) biochemical relationships.

RESPONSIBILITIES:

• Collaborate with R&D across various disease areas to analyze ‘omics data for better understanding of disease biology, preclinical model characterization, drug mechanism of action, biomarker identification, and contribute to the identification of new therapeutic targets
• Provide input as needed to experimental groups to guide study design for ‘omics-based experiments
• Use expertise as a computational biologist to integrate data from diverse sources (including transcriptome, proteome, DNA sequencing, genome structure data, and other NGS platforms)
• Work in cross-disciplinary teams and effectively communicate findings to scientific audiences with broad range of backgrounds, including biology, chemistry, and statistics
• Generalize pipelines for data integration and analysis
• Organize and document analysis strategies and results

REQUIREMENTS:

• Ph.D. in Computational Biology, Biological Sciences, Bioinformatics, Biostatistics, or related fields, plus 2+ years of post-PhD experience (Senior Scientist) or 3+ years of industry (Assistant Director)
• Strong track record of innovative research demonstrated in publications and oral presentations
• Familiarity with methods for advanced omics analysis such as single cell omics analysis, network inference and analysis, and machine learning
• Proficiency with Linux, git and scripting languages such as Python or R, and analytical environments/IDEs such as Jupyter, RStudio, or VSCode. Familiarity with AWS/Cloud compute is a plus.
• Excellent oral and written communication skills
• An ability to be productive and successful in a fast-paced work environment
• Knowledge in Cardiovascular, Renal, Pulmonary or Neurology fields is preferred

Ionis offers an excellent benefits package! Follow this link for more details: Ionis Benefits

Full Benefits Link: https://ionis.com/careers#:~:text=Highly%20competitive%20benefits

The pay scale for the Senior Scientist level is $137,666 to $178,246

The pay scale for the Assistant Director level is $153,940 to 211,080

NO PHONE CALLS PLEASE. PRINCIPALS ONLY.

Ionis Pharmaceuticals, Inc. and all its subsidiaries are proud to be EEO employers.