Frontier AI Drug Discovery Challenge Architect

Mercor; United States; Remote; USD 83,000 - 138,000; Part time

Benefits offered by this job

Claude Max subscription reimbursed

Job summary

Mercor is seeking a research-focused designer to craft an evaluation framework for frontier AI models in drug discovery. You will design challenging problems, assemble a source-grounded data room, and write a rigorous grader.

You will validate and revise the framework, ensuring defensible conclusions even when data are incomplete or misleading. The role requires domain expertise at the PhD level or equivalent industry track record, with the ability to defend the reasoning process and judge the

Qualifications

• PhD or equivalent track record in mechanistic enzymology, structure-guided design, fragment-based discovery, or structure-based medicinal chemistry.
• Ability to pose rigorously defendable problems that resist shortcut solutions.
• Strong judgment of reasoning quality, not just final answers.

Responsibilities

• Design the challenge — identify the hidden basin and forcing chain that makes one conclusion inevitable.
• Build the world — assemble a data room from real, source-grounded data with traceable decisive values.
• Write the grader — produce a scoring document focused on substance over method.
• Validate it — perform verification and calibration before submission.
• Revise it — own rework if reviewer requests changes.

Skills

Mechanistic enzymology

Structure-guided design

Fragment-based discovery

Structure-based medicinal chemistry

Education

PhD or equivalent industry track record

Tools

Claude Code

Claude Max

Job description

Mercor is seeking a research-focused designer to craft an evaluation framework for frontier AI models in drug discovery. You will design challenging problems, assemble a source-grounded data room, and write a rigorous grader.

You will validate and revise the framework, ensuring defensible conclusions even when data are incomplete or misleading. The role requires domain expertise at the PhD level or equivalent industry track record, with the ability to defend the reasoning process and judge the