Fermentation Scientist: Scale-Up & Streptomyces Expert

Oath; Vacaville (CA); Hybrid; USD 100,000 - 130,000; Full time

Benefits offered by this job

Health insurance

Paid time off

Stock options

Job summary

Oath is seeking a Fermentation Scientist to develop, optimize, and scale microbial processes across SmF, SSF, and DSP, with a focus on Streptomyces, translating lab work into robust manufacturing.

Hybrid role at Oath's Vacaville, CA site. PhD with 1–5 years’ experience; travel up to 10%. Compensation is $100,000–$130,000/year plus equity. Benefits include health insurance, PTO, and stock options.

Qualifications

• PhD with 1–5 years of relevant industry experience in microbiology, biotech, biochemical engineering, or related fields.
• Hands-on experience with submerged liquid and solid-state fermentation.
• Experience cultivating Streptomyces or related microorganisms.
• Experience with downstream processing (DSP) and biomass/product recovery.
• Ability to travel up to 10% domestically and internationally.

Responsibilities

• Develop and optimize submerged liquid and solid-state fermentation processes.
• Design and execute fermentation experiments from bench scale through scale‑up.
• Develop robust cultivation processes for Streptomyces and other microbial strains.
• Optimize media, inoculum strategies, growth conditions, productivity, yield, and process consistency.
• Develop DSP approaches for microbial biomass and product recovery.
• Troubleshoot fermentation and DSP performance and identify drivers of variability.
• Support process scale‑up and tech transfer to internal manufacturing teams and external CDMOs.
• Create process documentation, batch records, and technical reports.
• Analyze data and translate findings into actionable improvements.
• Collaborate with microbiology, formulation, manufacturing, quality, and external partners.

Skills

Fermentation science

Microbiology

Scale-up

Tech transfer

Vendor management

Travel willingness

Data analysis

Education

PhD in microbiology/biotech

Tools

Google Suite

Excel

Slack

Job description

Oath is seeking a Fermentation Scientist to develop, optimize, and scale microbial processes across SmF, SSF, and DSP, with a focus on Streptomyces, translating lab work into robust manufacturing.

Hybrid role at Oath's Vacaville, CA site. PhD with 1–5 years’ experience; travel up to 10%. Compensation is $100,000–$130,000/year plus equity. Benefits include health insurance, PTO, and stock options.