FDA Fellowship - Computational Toxicology

Oak Ridge Institute for Science and Education; Silver Spring (MD); In loco; USD 50.000 - 65.000; Tempo pieno

Descrizione del lavoro

FDA CDER/OTS in Silver Spring, MD, through the Oak Ridge Institute for Science and Education, offers a full-time fellowship to develop QSAR models and analyze toxicology data. You will learn to harvest and interpret data, build training databases, and communicate research results to internal and external stakeholders.

The program emphasizes data-mining, literature data extraction, and model development, with mentorship and a pathway to scholarly contributions.

Competenze

• Doctoral degree or current doctoral candidate with completion by 7/31/2026.
• Degree must be received within five years of the start date.
• Disciplines include Chemistry, Materials Sciences, Computer/Info/Data Sciences, Life Health and Medical Sciences, Mathematics and Statistics, Physics.

Mansioni

• Harvest and interpret toxicology data and develop QSAR models.
• Learn to apply data-mining tools and harmonize literature data.
• Construct knowledge bases and communicate results to stakeholders.

Conoscenze

Data mining

QSAR modeling

Data interpretation

Formazione

Doctoral degree in a relevant field

Pursuing doctoral degree with anticipated completion by July 31, 2026

Descrizione del lavoro

Organization

U.S. Food and Drug Administration (FDA)

Reference Code

FDA-CDER-2026-0103

Application Deadline

12/4/2026 3:00:00 PM Eastern Time Zone

Description

• Applications will be reviewed on a rolling-basis.

FDA Office and Location

A research opportunity is currently available at the U.S. Food and Drug Administration (FDA), Center for Drug Evaluation and Research (CDER), Office of Translational Sciences (OTS) located in Silver Spring, Maryland.

The Center for Drug Evaluation and Research (CDER) performs an essential public health task by making sure that safe and effective drugs are available to improve the health of people in the United States. As part of the U.S. Food and Drug Administration (FDA), CDER regulates over-the-counter and prescription drugs, including biological therapeutics and generic drugs. These efforts cover more than just medicines.

Research Project

This research project aims to develop quantitative structure-activity relationship (QSAR) models. The selected participant will learn to harvest and interpret toxicology data, develop and apply QSAR models, and communicate research results to both internal and external stakeholders.

Learning Objectives

• Learning to develop and apply data-mining tools
• Reviewing, extracting, and harmonizing data from literature
• Constructing and enhancing training databases for modeling purposes
• Learning to develop, validate and optimize (Q)SAR models
• Constructing chemical structure-linked knowledge bases

Mentor

The mentor for this opportunity is Lidiya Stavitskaya. If you have questions about the nature of the research, please contact [e-mail].

Anticipated Appointment Start Date

July 2026. Start date is flexible and will depend on a variety of factors.

Appointment Length

The appointment will initially be for one year, but may be renewed upon recommendation of FDA and is contingent on the availability of funds.

Level of Participation

The appointment is full-time.

Participant Stipend

The participant will receive a monthly stipend commensurate with educational level and experience.

Citizenship Requirements

This opportunity is available to U.S. citizens, Lawful Permanent Residents (LPR), and foreign nationals. Non-U.S. citizen applicants should refer to the Guidelines for Non-U.S. Citizens Details page of the program website for information about the valid immigration statuses that are acceptable for program participation.

This program, administered by ORAU through its contract with the U.S. Department of Energy to manage the Oak Ridge Institute for Science and Education, was established through an interagency agreement between DOE and FDA. The participant will receive a monthly stipend commensurate with educational level and experience. Proof of health insurance is required for participation in this program. Participants do not become employees of FDA, DOE or the program administrator, and there are no employment-related benefits.

Completion of a successful background investigation by the Office of Personnel Management is required for an applicant to be on-boarded at FDA. OPM can complete a background investigation only for individuals, including non-US Citizens, who have resided in the US for a total of three of the past five years.

FDA Ethics Requirements

If an ORISE Fellow, to include their spouse and minor children, reports what is identified as a Significantly Regulated Organization (SRO) or prohibited investment fund financial interest in any amount, or a relationship with an SRO, except for spousal employment with an SRO, and the individual will not voluntarily divest the financial interest or terminate the relationship, then the individual is not placed at FDA. For additional requirements, see FDA Ethics for Nonemployee Scientists.

Education

• Non-employee nature of the ORISE appointment;
• Prohibition on ORISE Fellows performing inherently governmental functions;
• Obligation of ORISE Fellows to convey all necessary rights to the FDA regarding intellectual property conceived or first reduced to practice during their fellowship;
• The fact that research materials and laboratory notebooks are the property of the FDA;
• ORISE fellow’s obligation to protect and not to further disclose or use non-public information.

Qualifications

The qualified candidate should have received a doctoral degree in one of the relevant fields or be currently pursuing a doctoral degree with anticipated completion by July 31, 2026. Degree must have been received within five years of the appointment start date.

Point of Contact

Ashley

Eligibility Requirements

• Degree: Doctoral Degree received within the last 60 months or anticipated to be received by 7/31/2026 11:59:00 PM.
• Discipline(s): Chemistry and Materials Sciences
• Computer, Information, and Data Sciences
• Life Health and Medical Sciences
• Mathematics and Statistics
• Physics

Affirmation

I am a U.S. citizen, or I have lived in the United States for at least 36 months (36 months do not have to be consecutive).
and
I have read the FDA Ethics Requirements.