Expert Science & Technology, Analytical Development, Potency and Flow

Biopharma Careers; East Hanover (NJ); On-site; USD 94,000 - 174,000; Full time

Benefits offered by this job

Health, life and disability benefits

401(k) with company match

Generous time off (vacation, personal,

holidays and leaves)

Job summary

Novartis in East Hanover, NJ is seeking an Expert Science & Technology professional to develop, optimize, and implement analytical methods for CAR-T cell therapy products. The role collaborates with Process Development, QA, and Manufacturing Sciences to meet timelines while ensuring data integrity.

The candidate should have 3+ years in industry or academia, experience with flow cytometry, ELISA, and mammalian cell culture, and a strong ability to communicate across cross-functional teams.

Qualifications

• Education: BA/BS or MS in biology, chemistry, biochemistry, microbiology or related science.
• 3 years of experience in industry or academia.
• Experience with cellular-based analytical methods (ELISA, cell-based assays).
• Aseptic technique and mammalian cell culture expertise (suspension cells).
• GMP experience is a plus.

Responsibilities

• Plan, organize, perform and document experiments under moderate supervision.
• Perform analytical testing including flow cytometry and cell-based bioassays.
• Review and approve data generated by team members.
• Maintain precise electronic lab records in compliance with Quality standards.
• Identify opportunities to improve methods and drive project timelines.

Skills

Flow cytometry

Cell culture

ELISA

SOP writing

Data analysis

GMP

Communication

Documentation

Education

BA/BS or MS in biology, chemistry, biochemistry, microbiology or related science

Job description

Location

East Hanover, US #onsite, 5x week*Novartis will not sponsor visas for this position.Novartis is unable to offer relocation support for this role: please only apply if this location is accessible for you.

Role Purpose

Bench to bedside! This exciting role serves as an Expert Science & Technology to develop, optimize, and implement novel analytical methodologies for our CAR-T cell therapy products. The successful candidate will work with a talented and experienced team in our Technical Research and Development organization at East Hanover, New Jersey. The successful candidate will be an important part of the potency and flow team, participating in analytical method development, qualification, and method transfer activities within the department. In addition, this role may also execute analytical assays to understand/characterize the function of our cell therapy products. He/ She will interface regularly and build relationships with other functions such as Process Development, Quality Control and Manufacturing Sciences & Technology to collaboratively drive projects to meet the established timelines while maintaining the highest quality and data integrity standards. This individual will uphold Novartis Values & Beliefs and Code of Ethics to successfully support our bold mission of delivering effective CAR-T cell products for patients in need.

Responsibilities

• This position requires strong organizational and scientific technical skills and experience with the routine handling of cells in culture.
• Plan, organize, perform and document scientific experiments under moderate supervision.
• Perform analytical testing including flow cytometry, and cell based bioassays including cytokine release, cytolytic activity and proliferation following appropriate SOPs and procedures.
• Review and approve data generated by other team members.
• Record and maintain meticulous records in electronic laboratory notebook in compliance with Quality standards.
• Identify opportunities for method improvement and execute optimization of analytical methods\Drive project timelines and deliverables while meeting internal quality and data integrity requirements.
• Communicate effectively and present complex data within the department and cross-functionally.
• Author and review method related technical documents to ensure completeness, accuracy, consistency and clarity.
• Support lab management including inventorying, clinical sample cryopreservation, sample management

Requirements

Education: BA/BS or MS in biology, chemistry, biochemistry, microbiology or other related science, plus a minimum of 3 year of prior experience in industry or academia.

• Scientific curiosity
• Understanding of the scientific principles underpinning of cellular based analytical methods including ELISA and Cell-based assays
• Expertise with aseptic technique and mammalian cell culture including suspension cells.
• Human T-cell culture experience is a plus
• Ability to communicate clearly with a variety of cross-functional teams
• Detail-oriented with expertise in problem solving and solid decision-making abilities
• Established ability to work in a regulated enviornment
• Good presentation skills and scientific/technical writing skills
• Must have good work ethic and demonstrated ability to work collaboratively within a large team and individually
• Experience writing laboratory SOPs and technical instructions is preferred
• Experience with GMP is a plus

The salary for this position is expected to range between $93,800 and $174,200 per year.The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors.

Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards.

• US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits.
• In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves.