Executive Medical Monitor — Oncology Clinical Development Leader

Agenus; Lexington (MA); On-site; USD 190,000 - 260,000; Full time

Job summary

RPMGlobal in Lexington, MA is seeking an Executive Medical Director, Medical Monitor to lead medical oversight of clinical trials, ensure patient safety, protocol integrity, and scientific rigor throughout study conduct.

You will collaborate across Clinical Development, Regulatory Affairs, Biostatistics, and Operations to interpret data, shape development plans, contribute to regulatory submissions, and drive data-driven decisions in oncology programs.

Qualifications

• MD or international equivalent with clinical research experience (5+ years).
• Significant biotechnology/pharmaceutical industry experience in Medical Monitor or sponsor-side clinical development.
• Oncology drug development experience required; immuno-oncology or immune-based therapies preferred.
• Experience leading programs from early phase to registrational studies and regulatory submissions.

Responsibilities

• Act as Medical Monitor for assigned trials, providing medical oversight to ensure patient safety, protocol compliance, and scientific integrity.
• Lead ongoing review, curation, interpretation, and analysis of clinical trial data to inform development decisions.
• Author/review key documents and participate in regulatory submissions and scientific forums.
• Collaborate cross-functionally with Clinical Operations, Regulatory Affairs, Biostatistics, and Pharmacovigilance to enable efficient study execution.
• Engage with external experts and senior leadership, communicating complex findings and recommendations.

Skills

MD

Oncology drug development

Immuno-oncology

Regulatory submissions

Clinical development leadership

Education

MD or international equivalent

Job description

RPMGlobal in Lexington, MA is seeking an Executive Medical Director, Medical Monitor to lead medical oversight of clinical trials, ensure patient safety, protocol integrity, and scientific rigor throughout study conduct.

You will collaborate across Clinical Development, Regulatory Affairs, Biostatistics, and Operations to interpret data, shape development plans, contribute to regulatory submissions, and drive data-driven decisions in oncology programs.