Executive Medical Director, Global Clinical Development

Scorpion Therapeutics; Lexington (MA); On-site; USD 250,000 - 350,000; Full time

Job summary

Agenus in Lexington, MA seeks an Executive Medical Director, Medical Monitor to oversee safety and data integrity across immuno-oncology programs. You will lead review of safety data, guide protocol safety, and collaborate with Clinical Operations, Data Management, and Regulatory Affairs.

The role combines hands-on oversight with strategic development plans, authoring regulatory documents and supporting submissions.

Qualifications

• MD or equivalent with 5+ years of clinical research experience.
• Strong background in oncology drug development, especially immuno-oncology, checkpoint inhibitors, or immune-based therapies.
• Proven leadership in early and late-phase clinical programs, including Phase 3 and regulatory submissions.

Responsibilities

• Act as Medical Monitor, review safety and clinical data.
• Develop clinical development plans.
• Author and review key regulatory documents.
• Collaborate across Clinical Operations, Data Management, and Regulatory Affairs.

Skills

Immuno-oncology

Clinical development

Regulatory submissions

Data interpretation

Cross-functional leadership

Medical Monitor

Education

MD or equivalent

Job description

Role:

Executive Medical Director, Medical Monitor, leading clinical trial oversight in immuno-oncology at Agenus.

Objectives:

ensure patient safety, scientific integrity, and data quality across clinical programs; support regulatory submissions and external scientific engagement.

Responsibilities:

act as Medical Monitor, review safety and clinical data, develop clinical development plans, author and review key regulatory documents, and collaborate across functions including Clinical Operations, Data Management, and Regulatory Affairs.

Requirements:

MD or equivalent with 5+ years of clinical research experience; strong background in oncology drug development, especially immuno-oncology, checkpoint inhibitors, or immune-based therapies; proven leadership in early and late-phase clinical programs, including Phase 3 and regulatory submissions.

High-Value:

immuno-oncology, checkpoint inhibitors, clinical development from early to late-stage, regulatory interactions, data interpretation, cross-functional collaboration.

WorkSetup:

not specified; role appears to be a hands-on, leadership position within a fast-paced biotech environment.