Executive Director, Early Clinical Development

Scorpion Therapeutics; California (MO); On-site; USD 250,000 - 350,000; Full time

Job summary

Revolution Medicines seeks an Executive Director of Early Clinical Development to lead planning and execution of clinical programs for RAS(ON) inhibitors in oncology. The role drives strategy, cross-functional collaboration, and regulatory interactions to advance programs from early trials toward regulatory submissions.

The candidate will oversee design and execution, align scientific goals with regulatory requirements, and manage key stakeholders while delivering milestones in a fast-paced

Qualifications

• MD, PhD, or equivalent with 13+ years in pharma/biotech or academia.
• Extensive experience in clinical trial design, early-phase drug development (Phase 1), regulatory interactions, and multi-disciplinary leadership.
• Strong knowledge of GCP, ICH, FDA, EMA guidelines.

Responsibilities

• Oversee clinical trial design, site management, data interpretation, regulatory interactions, and cross-functional team leadership.
• Develop and implement development strategies aligned with scientific and regulatory goals.
• Manage stakeholder relationships and ensure milestone achievement from early trials to potential regulatory submissions.

Skills

Strategic leadership

Cross-functional leadership

Regulatory knowledge

GCP/ICH knowledge

Communication

Data interpretation

Pharma/biotech experience

Education

MD/PhD or equivalent

Job description

Role

Executive Director of Early Clinical Development, leading the strategic planning and operational execution of clinical programs for Revolution Medicines' RAS(ON) inhibitors in oncology.

Responsibilities

• Oversee clinical trial design, site management, data interpretation, regulatory interactions, and cross-functional team leadership


• Develop and implement development strategies aligned with scientific and regulatory goals


• Manage stakeholder relationships and ensure milestone achievement from early trials to potential regulatory submissions

Requirements

• MD, PhD, or equivalent with 13+ years in pharma/biotech or academia


• Extensive experience in clinical trial design, early-phase drug development (Phase 1), regulatory interactions, and multi-disciplinary leadership


• Strong knowledge of GCP, ICH, FDA, EMA guidelines


• Proven track record of successful clinical development and regulatory submissions


• Excellent strategic, communication, and leadership skills

Preferred

• Experience with NDA/BLA submissions, regulatory authority interactions, phase IV studies, and process improvements


• Demonstrated ability to serve as a company spokesperson and lead enterprise-level initiatives

HighValue

oncology, RAS pathway, novel targeted therapies, clinical-stage molecules, early to late-phase development, regulatory engagement, cross-functional collaboration, onsite Redwood City, CA; no explicit travel expectations stated.