Executive Director, Clinical Business Operations

BeiGene, Ltd.

United States

Remote

USD 272,000 - 352,000

Full time

14 days+
Application generator

Don’t send a generic resume — generate a resume and cover letter tailored to this exact role.

Get past ATS filters

Benefits offered by this job

Medical
Dental
Vision
401(k)
FSA/HSA
Life Insurance
Paid Time Off
Wellness

Job summary

BeOne Medicines Ltd. in the United States seeks a global operational strategy and governance leader to drive financial stewardship, compliance, and digital transformation across Clinical Business Operations.

You will oversee investigator budgets, site contracts, payments, and budget data hub, aligning regional execution with global governance and reporting to senior leadership. Lead a high-performing team, manage cross-country stakeholders, and advance automation and data-driven decision making

Qualifications

  • Bachelor’s degree or above, in Life Sciences, Medical Science/ Medical, Finance, Health Economics, or related fields.
  • 14+ years of experience in Clinical operations, or study start-up, clinical site budgets, clinical site contracts, within a pharmaceutical sponsor or CRO environment.
  • 20+ years of experience preferred.
  • Strong planning and organizational skills and the ability to effectively leading team in a dynamic environment with competing priorities.
  • Strong executive communication skills with ability to present data-driven insights to Senior leadership.
  • Solution-driven and results-focused, with a willingness to dive deep and take a hands-on approach to work.
  • Demonstrated ability to analyze complex financial data and translate insights into actionable guidance.
  • Experience working cross-functionally with Clinical Operations, Finance, Payments, and Legal stakeholders.
  • Advanced proficiency in Excel and data analytics tools; experience with budget systems and contract lifecycle management platforms preferred.
  • Good knowledge of ICH-GCP, pharmaceutical related regulations and laws.

Responsibilities

  • Own and monitor KPIs across investigator budgeting, site contracting, payments, and budget data governance functions.
  • Direct the development, review, negotiation, and timely execution of site budgets and clinical trial agreements.
  • Supervise the end-to-end site payment process and payment reconciliation process to ensure financial obligations are processed accurately.
  • Oversee the collection, validation, and maintenance of budget-related information within designated databases and systems.
  • Ensure all budget, contract, payment, and supporting operational documentation remains audit ready and compliant.
  • Maintain Sunshine reporting obligations and global transparency requirements.
  • Provide strategic oversight of outsourced vendors and external partners.
  • Establish strong partnerships with Corporate Finance to drive governance.
  • Oversee operational finances and team resources to stay within budgets and resource allocations.
  • Provide leadership and performance management to team members and drive automation initiatives.

Skills

Budget forecasting
Governance
Cross-functional leadership
Strategic planning
Financial analysis
Data analytics

Education

Bachelor’s degree in Life Sciences

Tools

PowerBI
CTMS
Veeva
Contract Lifecycle Management
SharePoint

Job description

General Description

BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer. As a global operational strategy and governance leader, drive operational excellence, financial stewardship, compliance, scalability, and digital transformation initiatives across Clinical Business Operations team. Oversee investigator budgets, site contracts, site payments, and budget data hub team to ensure precise budget forecasting, efficient site contract execution, timely and accurate site payments and budget data entry in databases. Responsible for CBO workforce planning, talent acquisition, succession planning, capability development, performance management, and fostering a high-performing, agile, and continuously improving team.

Essential Functions of the Job

Ensure alignment of regional execution strategies with global governance frameworks, including clear accountability models, decision-making processes, and issue escalation mechanisms across cross-functional and cross-country stakeholders. Establish and lead recurring governance cadences, including quarterly business reviews, escalation forums, and executive reporting to ensure risks, trends, and operational performance are proactively managed and communicated. Own and monitor key operational and financial performance indicators (KPIs) across investigator budgeting, site contracting, payments, and budget data governance functions, including but not limited to: Site contract cycle time and execution timeliness Budget forecast accuracy and forecast vs. actual variance Site payment timeliness and reconciliation accuracy Provide strategic oversight of investigator fee budget planning activities to support accurate financial forecasting. Direct the development, review, negotiation, and timely execution of site budgets and clinical trial agreements in alignment within Fair Market value principles, study requirements, company standards, and study start-up timelines to support efficient operational delivery. Supervise the end-to-end site payment process and payment reconciliation process to ensure financial obligations are processed accurately and in accordance with contractual terms and payment schedules. Oversee the collection, validation, and maintenance of budget-related information within designated databases and systems to support data integrity and accuracy. Ensure all budget, contract, payment, and supporting operational documentation remains audit ready and compliant with applicable regulatory, financial, and internal governance standards. Maintain oversight of Sunshine reporting obligations and global transparency requirements, ensuring appropriate processes, controls and stakeholder alignment are consistently implemented across regions. Provide strategic oversight of outsourced vendors and external business partners, including performance monitoring, service quality oversight, issue escalation, and governance. Establish strong partnerships with Corporate Finance to drive financial governance, including oversight of accruals, forecast versus actual, and reconciliation processes. Oversee operational finances and team resources to ensure activities remain within approved budgets and resource allocations. Provide leadership, guidance, and performance management to team members, fostering accountability, collaboration, and continuous improvement. Support implementation of automation tools and digital solutions to improve overall productivity.

Supervisory Responsibilities

Yes Computer Skills: Microsoft Office apps, PowerBI, or equivalent, CTMS, Contract Lifecycle Management System, Veeva, Sharepoint etc.

Education Required

Bachelor’s degree or above, in Life Sciences, Medical Science/ Medical, Finance, Health Economics, or related fields. 14+ years of experience in Clinical operations, or study start-up, clinical site budgets, clinical site contracts, within a pharmaceutical sponsor or CRO environment. 20+ years of experience preferred.

Other Qualifications
  • Strong planning and organizational skills and the ability to effectively leading team in a dynamic environment with competing priorities.
  • Strong executive communication skills with ability to present data-driven insights to Senior leadership.
  • Solution-driven and results-focused, with a willingness to dive deep and take a hands-on approach to work.
  • Demonstrated ability to analyze complex financial data and translate insights into actionable guidance.
  • Experience working cross-functionally with Clinical Operations, Finance, Payments, and Legal stakeholders.
  • Advanced proficiency in Excel and data analytics tools; experience with budget systems and contract lifecycle management platforms preferred.
  • Good knowledge of ICH-GCP, pharmaceutical related regulations and laws.
Travel

Yes, 10% Global Competencies

Our Global Competencies
  • Fosters Teamwork
  • Provides and Solicits Honest and Actionable Feedback
  • Self-Awareness
  • Acts Inclusively
  • Demonstrates Initiative
  • Entrepreneurial Mindset
  • Continuous Learning
  • Embraces Change
  • Results-Oriented Analytical Thinking/Data Analysis
  • Financial Excellence
  • Communicates with Clarity
Values and Culture

When we exhibit our values of Patients First, Driving Excellence, Bold Ingenuity and Collaborative Spirit, through our twelve global competencies below, we help get more affordable medicines to more patients around the world.

Salary Range

Salary Range: $271,800.00 - $351,800.00 annually BeOne is committed to fair and equitable compensation practices. Actual compensation packages are determined by several factors that are unique to each candidate, including but not limited to job-related skills, depth of experience, certifications, relevant education or training, and specific work location. Packages may vary by location due to differences in the cost of labor. Please note that the listed range reflects the base salary or hourly range only. Non-Commercial roles are eligible to participate in the annual bonus plan, and Commercial roles are eligible to participate in an incentive compensation plan. All Company employees have the opportunity to own shares of BeOne Medicines Ltd. stock because all employees are eligible for discretionary equity awards and to voluntarily participate in the Employee Stock Purchase Plan.

Benefits
  • Medical
  • Dental
  • Vision
  • 401(k)
  • FSA/HSA
  • Life Insurance
  • Paid Time Off
  • Wellness
Equal Opportunity Employer

We are proud to be an equal opportunity employer. BeOne does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, disability, national origin, veteran status or any other basis covered by appropriate law. All employment is decided on the basis of qualifications, merit, and business need. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Assistance Act of 1974, Title I of the Americans with Disabilities Act of 1990, and any other applicable federal, state or local laws, applicants who require reasonable accommodation in the job application process may contact accommodationsus@beonemed.com.

Company Overview

BeOne is a global oncology company that is discovering and developing innovative treatments that are more affordable and accessible to cancer patients worldwide. With a broad portfolio, we are expediting development of our diverse pipeline of novel therapeutics through our internal capabilities and collaborations. We are committed to radically improving access to medicines for far more patients who need them. Our growing global team of more than 11,000 colleagues spans six continents.

China Mainland Job Posting

At BeOne, how we work is just as important as the work we do. Below are our Values that determine the decisions we make and how we do things. Patients First Driving Excellence Bold Ingenuity Collaborative Spirit

Get your free, confidential resume review.

or drag and drop your file here.

Similar jobs

Similar jobs worth comparing

Associate Director, Clinical Costing Systems & Tools
Associate Director, Clinical Costing Systems & Tools

BeiGene, Ltd. • United States

Remote
USD 142,000 - 192,000
Associate Director, Global Clinical Study Management
Associate Director, Global Clinical Study Management

BeiGene, Ltd. • United States

Remote
USD 143,000 - 193,000
Medical insurance
Dental insurance
Vision insurance
+5
Executive Director, Head of Clinical Operations Excellence
Executive Director, Head of Clinical Operations Excellence

BeiGene, Ltd. • United States

Remote
USD 272,000 - 352,000
Director, Head of Patient Recruitment and Retention, Americas
Director, Head of Patient Recruitment and Retention, Americas

BeiGene, Ltd. • United States

Remote
USD 172,000 - 232,000
Benefits package including Medical, &
401(k) and Wellness programs
Senior Director Clinical Development, Breast Cancer
Senior Director Clinical Development, Breast Cancer

BeiGene, Ltd. • United States

Remote
USD 300,000 - 370,000
Medical benefits
Dental benefits
Vision benefits
+5
Director, Process Optimization Lead
Director, Process Optimization Lead

BeiGene, Ltd. • United States Virgin Islands

On-site
USD 172,000 - 232,000
Executive Director, Global Tax Reporting and Compliance
Executive Director, Global Tax Reporting and Compliance

BeiGene, Ltd. • United States

Remote
USD 284,000 - 364,000
Medical benefits
Dental benefits
Vision benefits
+5
Associate Director, Regional Clinical Study Management
Associate Director, Regional Clinical Study Management

BeiGene, Ltd. • United States

On-site
USD 143,000 - 193,000
Director, Global Medical Affairs, Omnichannel Transformation & Customer Experience
Director, Global Medical Affairs, Omnichannel Transformation & Customer Experience

BeiGene, Ltd. • United States

Remote
USD 192,000 - 252,000
Executive Director, Global Medical Affairs Disease Area Lead, Solid Tumors
Executive Director, Global Medical Affairs Disease Area Lead, Solid Tumors

BeiGene, Ltd. • United States

Remote
USD 297,000 - 377,000
Medical benefits
Dental benefits
Vision benefits
+3