Executive Director, Biologics Innovation & Strategy

Exelixis, Inc.; Alameda (CA); On-site; USD 268,500 - 380,500; Full time

Benefits offered by this job

401k plan with company contributions

Medical, dental and vision coverage

Life and disability insurance

Discretionary annual bonus

Job summary

Exelixis, Inc. is seeking an Executive Director to lead Biologics Innovation & Strategy in Alameda, CA. The role focuses on evaluating and advancing antibody-based therapeutics from discovery through IND, with oversight of translational pharmacology and early toxicology.

You will partner with PK, toxicology, translational medicine and development teams to shape program strategies and clinical indications. The position requires a Ph.D.

Qualifications

• Ph.D. with 15+ years in biotech/pharma post-Ph.D.
• Strong background in biologics, oncology focus essential.
• Experience leading antibody-based programs from discovery to IND.

Responsibilities

• Lead antibody-based therapeutic programs and IND sections.
• Collaborate across PK, toxicology, translational medicine and development teams.
• Manage external collaborations and translational sub-teams.
• Hire, mentor, and build Bio/Tox capabilities within Discovery Pharm/Tox.
• Drive project timelines and resource planning to meet program goals.
• Provide strategic direction for clinical indications and portfolio.
• Ensure IP strategy and regulatory documentation are robust.

Skills

Biologics Oncology

ADC/ Bispecifics

Translational pharmacology

IP filings

Education

Ph.D. in Pharmacology/ Biology/ Immunology

Job description

Executive Director, Biologics Innovation & StrategySkip to main contentCookies are essential for the operation of our website. By using our website, you agree to the use of necessary cookies. This website uses cookies and similar technologies to offer website functions, analyze site usage and other trends, and to provide advertising and marketing. By clicking “Accept Cookies,” you consent to the use of all the cookies and similar technologies. By clicking “Decline,” you may opt-out of all cookies and similar technologies other than strictly necessary cookies. For additional information, please review our Online Privacy Statement.# Search CareersExecutive Director, Biologics Innovation & Strategy page is loaded## Executive Director, Biologics Innovation & StrategyApplylocations: Alameda, CAtime type: Full timeposted on: Posted Yesterdayjob requisition id: JR6976**SUMMARY/JOB PURPOSE:**As a member of the biotherapeutics group, the incumbent plays a key role in leading and managing the efforts to evaluate drug candidates resulting from the Biologics discovery and development efforts at Exelixis from both an in vivo pharmacological perspective as well as relating to early research toxicology and safety. The incumbent supports the head of biotherapeutics in research and development activities of ongoing and new projects in the biologics' portfolio including providing leadership for post-DC Translational sub-teams, supporting efforts to identify clinical indications for projects, and maintaining responsibility for writing Pharmacology sections in the IND.**ESSENTIAL DUTIES AND RESPONSIBILITIES:*** Lead and execute antibody–based therapeutic programs.* Interact and collaborate with other biotherapeutics department team members, internal departments in development (pharmacokinetics, toxicology, translational medicine, pharmaceutical development) and external collaboration colleagues to discuss and resolve project needs and issues in research and early development of biotherapeutics.* Project lead in collaboration with scientific research and development. Participates in cross-functional teams to implement research plans.* Identify and manage critical path activities and resources for development candidate nomination.* Identify and manage interdependencies and hand-offs.* Identify and proactively mitigate roadblocks.* Lead and manage projects in external collaborations* Lead and oversee the design, execution, and analysis of in vivo studies to evaluate efficacy, PK/PD, and early toxicology assessments for biologics projects* Expand the Pharm/Tox function with new hires, and manage, guide, and train hires for in-house lab expansion in Discovery Pharm/Tox and project team leadership in biologics programs.* Accomplish goals under project team timelines* Provide support in the evaluation of biologics research platforms and preclinical licensing candidates as needed.* Maintain consistent, multi-level communication with Development Team Members, Senior Management, and the Executive Team.* Support, teach, and mentor co-workers* Follow company intellectual property and compliance policies and practices.* Comply with company health and safety policies and general laboratory practices.* Departmental activities such as budget planning, administrative management and employee performance development and planning if the position oversees internal employees.**SUPERVISORY RESPONSIBILITIES:*** Directly supervises employees**EDUCATION/EXPERIENCE/KNOWLEDGE & SKILLS:****Education/Experience:*** Doctoral degree (Ph.D.) in related scientific discipline such as Pharmacology, biology, immunology, biochemistry, molecular biology or microbiology and a minimum of fifteen years of experience in the biotechnology/pharmaceutical industry post Ph.D.; or,* Equivalent combination of education and experience**Experience/The Ideal for Successful Entry into Job:*** Strong background in biologics domain. Experience with biologics in Oncology is a must* Experience leading and managing Oncology/ ADC/ Programs* Research experience with antibody-based therapeutics from discovery to IND* Experience writing intellectual property filings, reports, and non-clinical IND sections**Knowledge/Skills:*** Extensive scientific knowledge in field biologics in Oncology and experience taking biologics projects from discovery to IND* Extensive knowledge of in vitro and in vivo characterization and translational pharmacology of ADCs and bispecifics* Knowledge of intellectual property matters, and issues related to biotherapeutics.* The knowledge to apply advanced scientific and technical principles, theories, and concepts, and contribute to the development of new principles and concepts.* Ability to set goals with an understanding of priority and impact to program, department, and organization.* Think strategically and solution oriented.* Take a hands-on, “roll up your sleeves” approach.* Ability to drive, facilitate, track, anticipate, influence, and implement team objectives; challenge the status quo where relevant.* Ability to resolve conflicts within the team**JOB COMPLEXITY:*** Works on extremely complex problems where analysis of situations or data requires an evaluation of intangible variables.* Exercises independent judgment in developing methods, techniques, and evaluation criteria for obtaining results.* Uses professional concepts to contribute to development of company concepts and principles and to achieve objectives in creative and effective ways.#LI-HG1### ### Our compensation reflects the cost of labor across several U.S. geographic markets, and we pay differently based on those defined markets. The base pay range for this position is $268,500 - $380,500 annually. The base pay range may take into account the candidate’s geographic region, which will adjust the pay depending on the specific work location. The base pay offered will take into account the candidate’s geographic region, job-related knowledge, skills, experience and internal equity, among other factors.In addition to the base salary, as part of our Total Rewards program, Exelixis offers comprehensive employee benefits package, including a 401k plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. Employees are also eligible for a discretionary annual bonus program, or if field sales staff, a sales-based incentive plan. Exelixis also offers employees the opportunity to purchase company stock, and receive long-term incentives, 15 accrued vacation days in their first year, 17 paid holidays including a company-wide winter shutdown in December, and up to 10 sick days throughout the calendar year.### If you have a disability and need an accommodation in relation to the application and/or recruitment process, please email us at: ***[e-mail]******.*** **WORKING CONDITIONS:**Our office is a modern space that fosters collaboration and creativity. Teams work closely together, sharing ideas and solutions in a supportive atmosphere. We provide all necessary equipment, including dual monitors and ergonomic chairs, to ensure a comfortable workspace. **DISCLAIMER:** The preceding job description has been designed to indicate the general nature and level of work performed by employees within this classification. It is not designed to contain or be interpreted as a comprehensive inventory of all duties, responsibilities and qualifications required of employees assigned to the job. ***We are an Equal Opportunity Employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity, status as a veteran, and basis of disability or any other federal, state or local protected class.***