Executive Assistant

Amylyx Pharmaceuticals, Inc.; Cambridge (MA); On-site; USD 120,000 - 135,000; Full time

Job summary

Amylyx Pharmaceuticals, Inc. is seeking an experienced Executive Assistant to provide high-level support to the CHRO and CTOO. You will manage complex calendars, coordinate meetings and travel across time zones, and help prepare materials and executive communications.

This role requires discretion with confidential information, collaboration across HR, Technical Operations, and Office Support, and regular on-site presence in our Cambridge, MA office at least once a week.

Qualifications

• 10+ years of Executive Assistant or senior administrative support experience.
• Strong organizational, planning, and prioritization skills.
• Advanced proficiency in Microsoft Office Suite.
• Ability to handle confidential information with discretion.

Responsibilities

• Provide high-level administrative support to the CHRO and CTOO; manage calendars and meeting logistics across time zones.
• Coordinate domestic and international travel arrangements, itineraries, and expense reporting.
• Prepare meeting materials, presentations, agendas, and executive communications.
• Anticipate executive needs and ensure timely follow-up on key actions.
• Support HR, Technical Operations, and vendor administration, including budgets and contracts.
• Collaborate with the Executive Administration team on events and onboarding activities.

Skills

Executive support

Calendar management

Travel coordination

Budget support

Vendor management

Discretion with confidential info

Education

Bachelors degree or equivalent

Tools

Microsoft Office Suite

LinkSquared

Workday

Concur

NetSuite

Job description

Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve. We are a clinical-stage company currently focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS).

Our mission is powered by our people. Our core values – be audacious, be curious, be authentic, be engaged, and be accountable – creating a culture of caring. Amylyx has assembled an experienced team ready to take action because the communities we serve have no time to wait. If you share our passion and are determined to tackle some of medicine’s toughest problems.

The Opportunity

The Executive Assistant will provide executive, operational, and administrative support to the CHRO and CTOO. Responsibilities include managing complex schedules, coordinating meetings and travel, supporting department budgets and vendor activities, facilitating employee engagement initiatives, and partnering across the organization to ensure smooth day-to-day operations.

On-site presence in our Cambridge, MA office is typically required at least one day per week. During busy times there may be more on-site presence required.

Responsibilities

Executive Support

Provide high-level administrative support to the CHRO and CTOO. Manage complex calendars, schedules, and meeting logistics across multiple stakeholders and time zones. Coordinate domestic and international travel arrangements, itineraries, and expense reporting. Prepare meeting materials, presentations, agendas, and executive communications. Anticipate executive needs, proactively manage priorities, and ensure timely follow-up on key actions. Handle highly confidential information with professionalism and discretion.

Human Resources, Technical Operations & Employee Experience

Support employee engagement and culture-building initiatives across the organization. Coordinate logistics and execution for Exchange Meetings, Anchor Weeks, employee recognition activities, leadership meetings, and company-wide events. Maintain HR-related communications, resources, and administrative processes. Coordinate vendor and contract administration activities for both Human Resources and Technical Operations, including purchase order management, invoice processing, contract routing, and maintaining related documentation within company systems. Support department budget administration and vendor relationships.

Collaboration & Office Support

Partner closely with the Executive Administration team to ensure seamless support across the organization. Collaborate on company events, leadership meetings, and special projects. Participate in regular onsite activities in the Cambridge office, including team meetings, employee engagement events, onboarding activities, and other key business initiatives, helping to foster a connected and collaborative workplace culture. Help foster a welcoming, professional, and collaborative workplace environment.

Required Qualifications

10+ years of Executive Assistant or senior administrative support experience, preferably supporting senior leaders. Exceptional organizational, planning, and prioritization skills. Strong written and verbal communication skills. Demonstrated ability to manage multiple priorities in a fast-paced environment. Advanced proficiency in Microsoft Office Suite. Proven ability to manage confidential and sensitive information with discretion.

Preferred Requirements

Experience in biotechnology, pharmaceutical, healthcare, or other highly regulated industries. Experience with purchase order processing, invoice management, vendor administration, and systems such as LinkSquared, Workday, Concur, NetSuite, or similar business applications. Bachelor's degree or equivalent combination of education and experience.

Work Location and Conditions

• At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations related to health insurance coverage and state tax regulations, we are unable to hire employees who reside and/or work in certain states. Currently, we are not considering applicants from Alaska, Arizona, Hawaii, Michigan and Tennessee.
• This role requires you to be present in our Cambridge MA office at least once weekly.
• You must have access to work in setting which enables meeting all requirements of the role (including privacy, reliable internet access, phone, ability to video conference, etc.) at your remote location.

Compensation

The pay range posted below represents our good faith estimate of compensation for this role, based on market data and internal benchmarks. The final offer may vary depending on a candidate’s experience, skills, and qualifications, as well as considerations of internal equity.

Estimated Pay Range

$120,000 - $135,000 USD

Amylyx Pharmaceuticals is an Equal Opportunity Employer that does not discriminate on the basis of actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, pregnancy-related conditions, and lactation), gender identity or expression (including transgender status), sexual orientation, marital status, military service and veteran status, physical or mental disability, genetic information, or any other characteristic protected by applicable federal, state, or local laws and ordinances. Amylyx’s management team is dedicated to this policy with respect to recruitment, hiring, placement, promotion, transfer, training, compensation, benefits, employee activities, access to facilities and programs, and general treatment during employment. Accommodations are available for candidates who require them in our selection process. If you need an accommodation, please let your Amylyx Talent Acquisition contact know. It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.