Entrepreneur in Residence

HIKE Venture Studio; Philadelphia (Philadelphia County); Hybrid; USD 120,000 - 180,000; Full time

Job summary

HIKE Venture Studio in Philadelphia, PA, seeks an Entrepreneur in Residence (EiR) to explore and validate new venture concepts in healthcare technology and infrastructure. This full-time hybrid role combines market research, customer discovery, and problem-solution testing with hands-on collaboration across embedded engineering pods.

You will draft product strategies, shape business models aligned with payer and enterprise needs, and develop go-to-market plans with fractional C-suite leaders.

Qualifications

• Experience in healthcare, health tech, or regulated industries is preferred.
• Strong skills in market research, customer discovery, and data-driven analysis.
• Proven ability to design business models, financial projections, and strategic plans.
• Ability to translate business goals into product roadmaps and technical requirements.
• Experience in fundraising, investor relations, or venture capital is a plus.

Responsibilities

• Engage with healthcare stakeholders to refine venture hypotheses.
• Draft product strategies and business models aligned with payer needs.
• Collaborate with embedded engineering pods to translate business goals into roadmaps.
• Develop go-to-market plans and operating frameworks for spin-out opportunities.
• Prepare investor and partner materials and support early product development activities.

Skills

Market research

Customer discovery

Financial modeling

Business model design

Fundraising

Strategic planning

Stakeholder communication

Education

MBA or relevant advanced degree (plus)

Job description

Company Description

HIKE Venture Studio co-builds healthcare companies built to succeed within the realities of regulated healthcare and to deliver products that payers will adopt. The studio partners with founders at the intersection of healthcare, technology, and infrastructure, focusing on care delivery, interoperability, operations, and security. HIKE embeds senior engineering teams, fractional C-suite leaders, and aligned capital directly into founding teams to accelerate growth and enterprise readiness. By working side by side with founders, HIKE helps build the technology, operating models, and security posture required to move from early product to payer-ready company. Founders are invited to pitch healthcare infrastructure concepts to HIKE via [e-mail].

Role Description

The Entrepreneur in Residence (EiR) is a full-time hybrid role based in Philadelphia, PA, with flexibility for some work from home. The EiR will explore and validate new venture concepts in healthcare technology and infrastructure, including market research, customer discovery, and problem-solution fit testing. This role involves designing and iterating on venture theses, drafting product strategies, collaborating with embedded engineering pods, and shaping business models aligned with payer and enterprise requirements. The EiR will work closely with fractional C-suite leaders to develop go-to-market plans, financial projections, and operating frameworks for potential spin-out companies. Day-to-day responsibilities include engaging with healthcare stakeholders, refining hypotheses through data and feedback, preparing investor and partner materials, and supporting early product and company-building activities across the studio portfolio.

Qualifications

• Experience in healthcare, health tech, or regulated industries, with understanding of care delivery, payers, and health system operations.
• Skills in market research, customer discovery, and data-driven analysis to validate venture concepts and size opportunities.
• Strengths in business model design, financial modeling, and strategic planning for early-stage companies.
• Ability to collaborate with engineering and product teams to translate business goals into product roadmaps and technical requirements.
• Experience in fundraising, investor relations, or venture capital, including preparing pitch materials and engaging with capital partners.
• Strong communication and storytelling skills to clearly articulate complex healthcare and infrastructure ideas to diverse stakeholders.
• Comfort operating in ambiguity, with a bias toward experimentation, rapid iteration, and evidence-based decision-making.
• Prior founder, startup operator, or intrapreneur experience is highly beneficial; MBA or relevant advanced degree is a plus but not required.
• Ability to work effectively in a hybrid environment, spending time in Philadelphia, PA with studio teams and founders while managing remote work when appropriate.