Enterprise Stroke Medical Director

Prisma Health; Greenville (SC); On-site; USD 350,000 - 550,000; Full time

Job summary

Prisma Health in Greenville, South Carolina, seeks an experienced Enterprise Stroke Medical Director to design and lead a high-performing, integrated stroke system of care. The role focuses on systemwide clinical and strategic leadership for stroke care, setting standards and optimizing outcomes across all Prisma Health markets.

The Director will develop a coordinated stroke network with stroke centers, telestroke, and EMS partnerships, advancing rapid diagnosis, treatment, and recovery while

Qualifications

• Board-certified in neurology with vascular neurology subspecialty preferred.
• Experience in leading stroke programs or systems of care.

Responsibilities

• Lead systemwide stroke care standards and pathways.
• Drive quality, access, and patient outcomes across Prisma Health markets.
• Oversee telestroke services, interfacility transfer protocols, and EMS partnerships.

Skills

Stroke neurology

Vascular neurology

Clinical leadership

Strategic planning

Job description

Enterprise Stroke Medical Director

Prisma Health | Greenville, South Carolina

Prisma Health, headquartered in Greenville, South Carolina, is seeking to recruit an experienced Endovascular or Vascular Neurology physician leader to serve as its Enterprise Stroke Medical Director. This senior leadership role offers a unique opportunity to design and advance a high-performing, integrated stroke system of care across one of the nation’s most innovative and rapidly growing health systems.

Reporting to the Chief of Neurology, the Enterprise Stroke Medical Director serves as the systemwide clinical and strategic leader for stroke care, with enterprise responsibility for advancing quality, access, integration, research, and innovation across all Prisma Health markets. This role is accountable for establishing clinical standards, aligning care pathways, and optimizing outcomes and patient experience across the full continuum of stroke care.

The position carries enterprise authority to develop and operationalize a coordinated stroke network, including Comprehensive and Primary Stroke Centers, telestroke services, interfacility transfer protocols, and partnerships with EMS and referring hospitals. The Director will lead efforts to ensure timely access to thrombectomy and advanced stroke therapies, reduce variability in care delivery, and build a high-reliability system focused on rapid diagnosis, treatment, and recovery.

A central focus of the role is leading system transformation through strategic planning, physician engagement, and multidisciplinary integration. The Director partners closely with neurosurgery, neurocritical care, neuroradiology, emergency medicine, rehabilitation, behavioral health, and operational leaders to build cohesive, high-performing teams and scalable care models across inpatient, outpatient, and ambulatory settings.

The Enterprise Stroke Medical Director also provides leadership for stroke-related clinical research and innovation, with the opportunity to expand clinical trials, industry collaboration, and academic partnerships. Prisma Health maintains strong affiliations with the University of South Carolina, Clemson University, and Furman University, offering a robust platform for academic engagement and program growth.

Prisma Health is South Carolina’s largest and most innovative health system and the state’s largest nongovernmental employer. The system is nationally recognized for excellence, ranking in the 98th percentile for employee satisfaction, named to Fortune’s America’s Most Innovative Companies list (2026), and recognized by Press Ganey as Health Care System of the Year (2026). Prisma offers a supportive, forward-looking culture built for physicians and healthcare leaders to thrive.

With nearly 30,000 team members, 18 hospitals, 2,984 beds, and more than 300 physician practice sites, Prisma Health serves more than 1.2 million unique patients annually. Its goal is to improve the health of all individuals we serve by advancing clinical quality, enhancing patient experience, expanding access, and leading in clinical research and education. Prisma Health is “Here for Good.”

Greenville, South Carolina offers an exceptional quality of life and serves a catchment area of 1.6 million people. Located along the I-85 corridor between Atlanta and Charlotte, the region is one of the fastest-growing in the country, with proximity to mountains, lakes, and coastal destinations, along with a vibrant cultural and economic environment.