Engineer II, CMC Development Operations

Moderna Therapeutics; Norwood (MA); Sur place; USD 74 000 - 118 000; Plein temps

Résumé du poste

Moderna is seeking an Engineer II on-site at our Norwood, MA Technology Center to support pilot-scale nucleic acid operations and tech transfer from bench to pilot scale. You will lead batches, troubleshoot in real time, and collaborate across Development, Analytical, and other groups to ensure robust, scalable processes.

The role emphasizes ownership of projects, documentation, safety, GDP compliance, and mentorship of junior team members in a fast-paced environment.

Qualifications

• Education: Bachelor's or Master's degree in Life Sciences, Chemistry, Engineering, Pharmaceutical Sciences, or related/relevant technical discipline.
• Experience: 2 years of relevant experience with a Bachelor's degree or minimal experience with a Master's degree.

Responsabilités

• Lead or contribute to technical projects related to DNA/RNA/LNP/DP processes, including technology transfer, process optimization, and continuous improvement initiatives.
• Serve as a batch lead supporting execution, propose troubleshooting in real time to ensure successful outcomes.
• Propose and implement solutions to technical challenges, gaps, and process deviations.
• Collaborate cross-functionally with Process Development, Analytical, and other teams to support tech transfer and process robustness.
• Distill and communicate batch-related data to inform process improvements and decision-making.
• Author and optimize technical documentation, including SOPs and protocols, and support training of team members.
• Provide operational leadership during batches, guide junior team members, and align stakeholders on project goals.
• Apply operational excellence principles to improve workflows, lab organization, and execution efficiency.
• Identify and mitigate risks, including safety, process, and operational risks; elevate when appropriate.
• Maintain compliance with GDP practices, safety procedures, and environmental regulations.

Connaissances

Process development

Operations

Troubleshooting

Technology transfer

Data analysis

Cross-functional collaboration

mRNA synthesis

LNP formulation

Team mentoring

Quality culture

Formation

Bachelor's degree

Master's degree

Description du poste

The Role:

The Operations Science and Technology team is seeking a highly skilled and motivated Engineer II to support pilot-scale nucleic acid and formulated nucleic acid product operations. This role is responsible for transferring processes from bench to pilot scale and generating DNA/RNA/LNP/DP for developmental and tox studiers, enabling first-time filings and commercial updates. This is an onsite role based in Moderna's Technology Center campus in Norwood, MA. In this role, you will execute independently while partnering cross-functionally to implement robust, scalable processes. You will take increasing ownership of technical projects, contribute to technology transfer activities, and proactively identify and resolve process challenges in a fast-paced environment.

Here’s What You’ll Do:

• Lead or contribute to technical projects with increasing ownership related to DNA/RNA/LNP/DP processes, including technology transfer, process optimization, and continuous improvement initiatives
• Serve as a batch lead supporting execution, propose troubleshooting in real time to ensure successful outcomes
• Propose and implement solutions to technical challenges, gaps, and process deviations
• Collaborate cross-functionally with Process Development, Analytical, and other teams to support tech transfer and process robustness
• Distill and communicate batch-related data to inform process improvements and decision-making
• Author and optimize technical documentation, including SOPs and protocols, and support training of team members
• Provide operational leadership during batches, guide junior team members, and align stakeholders on project goals
• Apply operational excellence principles to improve workflows, lab organization, and execution efficiency
• Identify and mitigate risks, including safety, process, and operational risks; elevate when appropriate
• Maintain compliance with GDP practices, safety procedures, and environmental regulations

Here’s What You’ll Need (Basic Qualifications)

Education: Bachelor's or Master's degree in Life Sciences, Chemistry, Engineering, Pharmaceutical Sciences, or related/relevant technical discipline.

Experience: 2 years of relevant experience with a Bachelor's degree or minimal experience with a Master's degree.

This position is site-based, requiring you to be at Moderna's site full-time. This position is not eligible for remote work.

Here’s What You’ll Bring to the Table (Preferred Qualifications)

• Advanced degree in Life Sciences, Chemistry, Engineering, Data Science, or a related technical discipline preferred.
• 2 to 3 years of relevant experience with a Master's degree, or 3 to 5 years of relevant experience with a Bachelor's degree preferred.
• Hands-on experience in process development or operations, including one or more: enzymatic reactions, chromatography, tangential flow filtration, formulation of biologics.
• Demonstrated ability to execute and troubleshoot processes independently in a fast-paced environment.
• Strong communication skills with the ability to collaborate effectively across cross-functional teams.
• Experience with mRNA/DNA synthesis, LNP formulation, and/or drug product processes.
• Experience in technology transfer and scale-up of processes.
• Demonstrated ability to own and drive technical projects or workstreams.
• Ability to analyze complex datasets and translate findings into actionable improvements.
• Proven ability to expand technical skillset and operate across multiple process areas.

Pay & Benefits

At Moderna, we believe that when you feel your best, you can do your best work. That’s why our benefits and well-being resources are designed to support you—at work, at home, and everywhere in between.

• Competitive healthcare, plus voluntary benefit programs to support your unique needs
• A holistic approach to well-being, with access to fitness, mindfulness, and mental health support
• Family planning benefits, including fertility, adoption, and surrogacy support
• Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown
• Savings and investments to help you plan for the future
• Location-specific perks and extras

The salary range for this role is $74,000.00 - $118,400.00. This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An individual's position within the salary range will be based on several factors including, but not limited to, specific competencies, relevant education, qualifications, certifications, experience, skills, performance, and business or organizational needs. The successful candidate may be eligible for an annual discretionary bonus, other incentive compensation, or equity award, subject to company plan eligibility criteria and individual performance.

About Moderna

Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world. By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities. We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.

Our Working Model

As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute, and make a meaningful impact. Moderna is a smoke-free, alcohol-free, and drug-free work environment.

Equal Opportunities

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. Moderna is a place where everyone can grow.

Moderna is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements.

Accommodations

We’re focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best. Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at [e-mail].

Export Control Notice

This position may involve access to technology or data that is subject to U.S. export control laws, including the Export Administration Regulations (EAR). As such, employment is contingent upon the applicant’s ability to access export-controlled information in accordance with U.S. law. Only U.S. persons (U.S. citizens, U.S. lawful permanent residents, asylees, or refugees) are currently eligible to access such information without an export license. Candidates who do not meet these criteria may still be considered, contingent on the company’s ability to obtain any required export control license.

Our Mission and Vision

At Moderna we are pioneering the development of a new class of drugs made of messenger RNA (mRNA). This novel drug platform builds on the discovery that modified mRNA can direct the body’s cellular machinery to produce nearly any protein of interest, from native proteins to antibodies and other entirely novel protein constructs that can have therapeutic activity inside and outside of cells. We have a clear mission to propel the field of mRNA science forward and deliver new medicines to patients and a unique vision for how to achieve this mission. Our Mission: To deliver on the promise of transformative messenger RNA (mRNA) science to bring new medicines to patients. Our Vision: To unlock the potential of mRNA by establishing an ecosystem of teams and partners that will work together to develop the broadest possible array of drugs, across diverse therapeutic areas and routes of administration, for serious diseases that are not treatable today.

Third Party Staffing Agencies

Moderna does not accept unsolicited resumes from any source other than directly from candidates. For the protection of all parties involved in the recruiting process, resumes will only be accepted from recruiters/agencies if a signed agreement is in place at the inception of the recruiting effort and authorized for a specified position. Unsolicited resumes sent to Moderna from recruiters/agencies do not constitute any type of relationship between the recruiter/agency and Moderna and do not obligate Moderna to pay fees if we hire from those resumes.

Reasonable Accommodation Notice

Moderna will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Applicants with disabilities may be entitled to reasonable accommodation under the terms of the Americans with Disabilities Act and certain state or local laws. Please inform the company's personnel representative by calling 617-460-9346 or emailing [e-mail] if you need assistance completing any forms or to otherwise participate in the application process. Examples of reasonable accommodation include making a change to the application process or work procedures, providing documents in an alternate format, using a sign language interpreter, or using specialized equipment.