Engineer

Amgen Inc. (IR); Thousand Oaks (CA); On-site; USD 88,281 - 119,439; Full time

Job summary

Amgen Inc. (IR) in Thousand Oaks, CA, is seeking a process engineer to lead and execute improvement efforts across manufacturing operations.

You will identify cycle time reductions, efficiency gains, and yield improvements while supporting system reliability and risk reduction strategies. The role requires a strong background in chemical/mechanical/bioengineering, experience in regulated environments, and hands-on work with manufacturing equipment (bioreactors, UFDF, filling lines).

Qualifications

• Bachelor’s or higher in chemical, mechanical, or bioengineering.
• Experience in regulated environments (FDA, cGMP, OSHA, EPA) preferred.
• Hands-on with complex manufacturing equipment and process optimization.
• Experience with drug substance manufacturing equipment (bioreactors, UFDF, filling, cleaning).
• Foundational knowledge of asset management systems for maintenance lifecycle.
• Fundamental process automation knowledge.
• Knowledge of DeltaV, Rockwell, and plant information systems is a plus.
• Strong independence, motivation, and organizational skills; good communicator.

Responsibilities

• Lead and execute process improvement projects to reduce cycle time and improve yield.
• Support reliability and operating efficiency of manufacturing equipment.
• Perform RCA and troubleshooting; guide engineering investigations.
• Assist with design, installation, startup, validation of process equipment.
• Translate requirements into engineering documentation; collaborate cross-functionally.
• Support safety and environmental health practices on site.

Skills

Leadership

Technical writing

Communication

Presentation skills

Independence

Team collaboration

Education

Master’s degree in engineering

Bachelor’s degree in chemical/mechanical/bioengineering

Associate’s degree in engineering

High school diploma / GED with engineering experience

Tools

Maximo

DeltaV

Rockwell Automation

Plant Information Systems

Job description

What you will do

Let’s do this. Let’s change the world. In this vital role you will lead and execute improvement efforts, including identifying cycle reduction time opportunities, efficiency gains, and yield improvement opportunities. Support system reliability and operational optimization efforts. Identify system performance risks (e.g. single point of failure or obsolescence) and implement risk reduction strategies. Lead and execute improvement efforts, including identifying cycle reduction time opportunities, efficiency gains, and yield improvement opportunities. Support technical investigations, root cause analysis, and equipment troubleshooting activities. Apply structured problem‑solving methodologies with guidance. Analyze data and assist in developing engineering solutions using data techniques and methodologies (e.g. Statistical Process Control, Six Sigma, predictive maintenance analysis, etc.). Support new technology introductions by assisting with engineering assessments, equipment modifications, and execution of engineering runs. Collect, organize, analyze, and present results for operational issues and engineering projects of small scope and complexity. Provide onsite day‑to‑day technical support for equipment and process troubleshooting. Apply process engineering principles to support the design, specification, installation, startup, and validation of process equipment and systems. Assist with project activities by performing engineering studies and assessments for process equipment systems. Translate user and process requirements into engineering documentation and support design development in alignment with standard engineering practices. Communicate effectively with supervisors, cross‑functional teams, and support staff to elevate issues and contribute to solutions. Support a safe working environment by aligning with all pertinent environmental health/safety practice, rules and regulations.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The professional we seek is a leader with these qualifications.

Basic Qualifications: Master’s degree OR Bachelor’s degree and 2 years of Engineering experience OR Associate’s degree and 6 years of Engineering experience OR High school diploma / GED and 8 years of Engineering experience.

• Bachelor’s degree in Chemical Engineering, Mechanical Engineering, or Bioengineering preferred.
• Direct experience with regulated environments (e.g. FDA, cGMP, OSHA, EPA, etc.) is preferred.
• Subject Matter Expert and hands‑on experience with complex manufacturing process equipment including sophisticated troubleshooting, reliability and performance improvements, and design optimization.
• Direct experience in equipment engineering and problem solving for drug substance manufacturing equipment (Bioreactors, UFDF, Filling Machines, Cleaning Systems).
• Have a foundational knowledge of Maximo or equivalent Asset Management System for managing equipment maintenance and asset lifecycle.
• Process automation knowledge – fundamental understanding of automation infrastructure.
• Knowledge of Delta V, Rockwell, and Plant Information Systems is a plus.
• Demonstrates independence, strong self‑motivation, and organization, with the ability to manage multiple priorities; effective in communication, facilitation, and collaboration.
• Demonstrates a strong team‑oriented mindset and actively contributes to a collaborative culture that supports effective decision‑making.
• Applies a continuous improvement mindset in daily activities and promotes a strong commitment to safety in all aspects of work.
• Demonstrates interest in continuous learning opportunities around new tools, techniques, and configurations to enhance their analytical abilities.
• Strong leadership, technical writing, and communication/presentation skills are required.

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well‑being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
• A discretionary annual bonus program, or for field sales representatives, a sales‑based incentive plan.
• Stock‑based long‑term incentives.
• Award‑winning time‑off plans.
• Flexible work models where possible.

Salary range

Salary Range 88,281.00USD -119,439.00 USD

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.