E11 Bio - Scientist I/II - Advanced Imaging

convergentresearch; Alameda (CA); On-site; USD 120,000 - 180,000; Full time

Job summary

E11 Bio in Alameda, California is seeking a mission-aligned Imaging Scientist to develop, optimize and scale light microscopy workflows for large-scale image acquisition. You will work across sample preparation, microscopy, image analysis, and engineering-driven technology development to improve throughput, quality, and robustness.

You will define QC metrics, troubleshoot bottlenecks, and evaluate new hardware to expand imaging capacity while collaborating closely with biology, hardware, and

Qualifications

• Experience with light microscopy and quantitative imaging workflows.
• Ability to translate experimental requirements into reliable, scalable imaging processes.
• Familiarity with automation and instrument performance optimization.

Responsibilities

• Develop, optimize and scale light microscopy workflows for large-scale image acquisition.
• Define quantitative imaging QC metrics and troubleshoot acquisition bottlenecks.
• Evaluate new hardware and microscopy approaches to increase imaging capacity.
• Collaborate with sample preparation, molecular biology, hardware and computational teams.

Job description

E11 Bio is on a mission to advance connectomics towards the scale of whole mammalian brains. We are a collaborative and interdisciplinary team of scientists and engineers engaged in a neuroscience moonshot project to develop a radical technology platform for scalable brain mapping. E11 Bio is a non-profit Convergent Research focused research organization located in Alameda, California, pursuing blue-skies neuroscience research yet operating like a nimble, tight-knit start-up. Read our technology roadmap.

We are seeking a mission-aligned Imaging Scientist to develop, optimize and scale light microscopy workflows for large-scale image acquisition. This role combines sample preparation, advanced microscopy, quantitative image analysis, and engineering-driven technology development with the goal of improving imaging quality and robustness.

You will optimize sample mounting and acquisition strategies, automation, and instrument performance to improve throughput, reproducibility, and data quality at scale. The role will also involve defining quantitative imaging QC metrics, troubleshooting acquisition bottlenecks, and evaluating new hardware and microscopy approaches that can increase imaging capacity. Working closely with sample preparation, molecular biology, hardware, and computational teams, you will help translate experimental requirements into reliable and scalable imaging workflows.

E11 Bio, LLC is an Equal Employment Opportunity employer that proudly pursues and hires a diverse workforce. We do not make hiring or employment decisions on the basis of race, color, religion or religious belief, ethnic or national origin, nationality, sex, gender, gender-identity, sexual orientation, disability, age, military or veteran status, or any other basis protected by applicable local, state, or federal laws or prohibited by Company policy. We strive for a healthy and safe workplace and strictly prohibit harassment of any kind.