Downstream Purification and Stability Scientist

Eurofins; Andover (MA); On-site; USD 33,000 - 36,000; Full time

Benefits offered by this job

Medical, Dental, Vision insurance

Life and disability insurance

401(k) with company match

Paid vacation and holidays

Job summary

Eurofins USA PSS Insourcing Solutions seeks a lab scientist to plan, execute, and document downstream purification unit operations and stability studies for DSIs. You will oversee aseptic sampling, temperature-controlled sample logistics, sample accessioning, and coordination with testing laboratories.

You will collaborate with senior scientists and engineers to qualify purification processes, troubleshoot deviations, and deliver high-integrity datasets that safeguard commercial supply.

Qualifications

• Bachelor's degree in Chemical Engineering with 0–3 years lab experience.
• Experience in downstream purification and aseptic sampling.
• Understanding of GDP and data integrity practices.

Responsibilities

• Plan, execute, and document lab-scale downstream purification operations.
• Manage stability programs including aseptic aliquoting and temperature-controlled logistics.
• Coordinate with testing laboratories and cross-functional teams.
• Maintain high-integrity datasets and inventory controls.

Skills

Column chromatography

Tangential Flow Filtration

Aseptic techniques

Sample management workflows

Protein quantification

Statistical analysis

GDP / data integrity

Communication skills

Education

Bachelor's Degree in Chemical Engineering

Tools

ÄKTA

Unicorn software

SoloVPE

UV-Vis spectrophotometry

JMP

Minitab

Advanced Excel

Job description

In this role, you will play a pivotal role in planning, executing, and documenting laboratory-scale downstream purification unit operations and drug substance intermediate (DSI) hold and stability studies. You will be directly responsible for the operational management of critical stability programs, including aseptic aliquoting, temperature-controlled sample logistics, sample accessioning, coordination with testing laboratories, and inventory management. You will work closely with senior scientists and engineers across the department and cross-functional teams to qualify purification processes, troubleshoot technical deviations, and deliver high-integrity datasets that safeguard commercial supply.

Key Skills Required:

• Demonstrated hands-on laboratory experience with bio-separation and downstream purification unit operations: column chromatography (ÄKTA / Unicorn software), Tangential Flow Filtration (UF/DF), and/or depth filtration.
• Rigorous understanding and demonstrated execution of aseptic techniques in biosafety cabinets (laminar flow hoods) for sterile sampling and aliquoting.
• Working knowledge of sample management workflows, inventory controls, and stability study execution.
• Familiarity with analytical tools for protein/biomolecule quantification (e.g., SoloVPE, UV-Vis spectrophotometry).
• Strong aptitude for statistical analysis, data handling, and experimental design (experience with JMP, Minitab, or advanced Excel is essential).
• High level of attention to detail and adherence to Good Documentation Practices (GDP) and data integrity principles.
• Excellent interpersonal, verbal, and written communication skills with the ability to articulate technical observations effectively within a matrixed team.

Bachelor's Degree in Chemical Engineering, Biochemical Engineering, Biotechnology, Biochemistry, Microbiology, Biology, or a related bioprocess discipline with 0-3 years of directly applicable bioprocess laboratory experience (or Master's degree with 0-1 year of experience).

The position is full-time, Monday-Friday, 8:00am-5:00pm, with overtime as needed. Candidates living within a commutable range of Andover, MA are encouraged to apply.

Comp: $24-26/hr

• Excellent full time benefits including comprehensive medical coverage, dental, and vision options
• Life and disability insurance
• 401(k) with company match
• Paid vacation and holidays

Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer.