Downstream CQV Engineer - 173962 - 174862 - 175087

Piper Companies; Holly Springs (MS); On-site; USD 100,000 - 140,000; Full time

Job summary

Piper Companies is seeking a Downstream CQV Engineer to join its life sciences manufacturing team in Holly Springs, NC. This onsite 6-month contract role focuses on commissioning and qualification of downstream systems, utilities, and large-scale equipment across multiple suites.

Responsibilities include CQV execution, document turnover, and cross-functional coordination with engineering, operations and quality to maintain project timelines and regulatory compliance.

Qualifications

• 2–10 years hands-on CQV/validation experience in large-scale manufacturing.
• Experience with downstream processing equipment; ultrafiltration preferred.
• Mechanical or engineering background with ability to inspect, troubleshoot, and work with equipment.
• Familiarity with installation verification, utilities qualification, and system turnover processes.
• Experience with electronic validation systems (e.g., Kneat) is a plus.

Responsibilities

• Execute CQV activities for downstream manufacturing systems and utilities.
• Review drawings, P&IDs, and system documentation to support verification.
• Perform hands-on testing, troubleshooting, and field walkdowns for large-scale equipment.
• Collaborate with engineering, operations, and quality teams to resolve issues and meet timelines.
• Assist in development and turnover documentation ensuring regulatory compliance.

Skills

CQV experience

Hands-on testing

Troubleshooting

Mechanical engineering

System turnover

Education

Mechanical engineering degree

Bachelor's in engineering

Tools

Kneat

P&IDs

Job description

Piper Companies is seeking a Downstream CQV Engineer to join a growing organization within the life sciences and biopharmaceutical manufacturing industry. This is an onsite, 6-month contract role with potential extensions, based in Holly Springs, NC. The Downstream CQV Engineer will support large-scale manufacturing operations with a primary focus on downstream systems, utilities, and commissioning and qualification activities across a multi-building production environment.

Responsibilities of the Downstream CQV Engineer:

• Execute commissioning, qualification, and verification (CQV) activities for downstream manufacturing systems and utilities
• Support installation verification and field execution through the review of drawings, P&IDs, and system documentation
• Perform hands‑on testing, troubleshooting, and field walkdowns for large-scale equipment including pumps, filters, valves, and piping systems
• Collaborate with engineering, operations, and quality teams to resolve issues and maintain project timelines across multiple manufacturing suites
• Assist in the development and completion of electronic documentation and turnover packages, ensuring compliance with internal and regulatory standards

Qualifications for the Downstream CQV Engineer:

• 2–10 years of hands‑on experience in CQV, validation, or engineering within large-scale manufacturing environments
• Experience working with downstream processing equipment; ultrafiltration experience strongly preferred
• Mechanical or engineering‑focused background with the ability to inspect, troubleshoot, and work directly with equipment and instrumentation
• Familiarity with installation verification, utilities qualification, and system turnover processes
• Experience with electronic validation systems (e.g., Kneat) is a plus

Compensation for the Downstream CQV Engineer:

• Salary Range: $100,000 – $140,000/year (USD)
• Comprehensive Benefits: Medical, Dental, Vision, 401(k), and applicable sick leave

Keywords: CQV engineer, commissioning, qualification, validation, downstream processing, ultrafiltration, IV, P&IDs, utilities qualification, large scale manufacturing, biopharmaceuticals, GMP, mechanical engineering, process equipment, pumps, filters, valves, Kneat, system turnover, field execution, equipment qualification, biotech manufacturing, water systems, UF systems.

This position opened for applications on August 21st, 2026, and will remain open for at least 30 days from the posting date.