Downstream CQV Engineer - 173962

Piper Companies; Holly Springs (NC); On-site; USD 100,000 - 140,000; Full time

Benefits offered by this job

Medical

Dental

Vision

401(k)

Job summary

Piper Companies is seeking a Downstream CQV Engineer to join a growing biopharmaceutical manufacturing organization in Holly Springs, NC. This onsite, 6‑month contract focuses on downstream systems, utilities, and commissioning and qualification activities across a multi‑building production environment.

You will execute CQV activities, review drawings and P&IDs, perform field testing on pumps, filters, and piping, and collaborate with engineering, operations, and quality to keep projects on

Qualifications

• 2–10 years of hands-on CQV/validation experience in large-scale manufacturing.
• Experience with downstream processing equipment; ultrafiltration preferred.
• Mechanical or engineering background with ability to inspect, troubleshoot, and work directly with equipment.

Responsibilities

• Execute CQV activities for downstream manufacturing systems and utilities.
• Review drawings, P&IDs, and system documentation for installation verification.
• Perform hands-on testing and field walkdowns on large-scale equipment.
• Collaborate with engineering, operations, and quality to resolve issues and maintain project timelines.
• Assist in development and completion of electronic documentation and turnover packages per regulatory standards.

Skills

CQV experience

Validation

Engineering

Downstream processing

Troubleshooting

Education

Engineering degree

Tools

Kneat

Job description

Piper Companies is seeking a Downstream CQV Engineer to join a growing organization within the life sciences and biopharmaceutical manufacturing industry. This is an onsite, 6‑month contract role with potential extensions, based in Holly Springs, NC. The Downstream CQV Engineer will support large‑scale manufacturing operations with a primary focus on downstream systems, utilities, and commissioning and qualification activities across a multi‑building production environment.

Responsibilities of the Downstream CQV Engineer:

• Execute commissioning, qualification, and verification (CQV) activities for downstream manufacturing systems and utilities
• Support installation verification and field execution through the review of drawings, P&IDs, and system documentation
• Perform hands‑on testing, troubleshooting, and field walkdowns for large‑scale equipment including pumps, filters, valves, and piping systems
• Collaborate with engineering, operations, and quality teams to resolve issues and maintain project timelines across multiple manufacturing suites
• Assist in the development and completion of electronic documentation and turnover packages, ensuring compliance with internal and regulatory standards

Qualifications for the Downstream CQV Engineer:

• 2-10 years of hands‑on experience in CQV, validation, or engineering within large‑scale manufacturing environments
• Experience working with downstream processing equipment; ultrafiltration experience strongly preferred
• Mechanical or engineering‑focused background with the ability to inspect, troubleshoot, and work directly with equipment and instrumentation
• Familiarity with installation verification, utilities qualification, and system turnover processes
• Experience with electronic validation systems (e.g., Kneat) is a plus

Compensation for the Downstream CQV Engineer:

• Salary Range: $100,000 - 140,000/year (USD)
• Comprehensive Benefits: Medical, Dental, Vision, 401(k), and applicable sick leave

Keywords: CQV engineer, commissioning, qualification, validation, downstream processing, ultrafiltration, IV, P&IDs, utilities qualification, large scale manufacturing, biopharmaceuticals, GMP, mechanical engineering, process equipment, pumps, filters, valves, Kneat, system turnover, field execution, equipment qualification, biotech manufacturing, water systems, UF systems.

This position opened for applications on August 21st, 2026, and will remain open for at least 30 days from the posting date.

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