Director, Statistical Programming

AstraZeneca GmbH; Waltham (MA); On-site; USD 169,000 - 253,000; Full time

Job summary

AstraZeneca Oncology Biometrics seeks a Statistical Programming Director to provide strategic leadership and line management for the Early Oncology Programming group. You will mentor programmers, ensure high-quality deliverables, and drive continuous improvement across outsourced and internal projects.

You will collaborate with Data Management, Biostatistics, Epidemiology, and Clinical Operations on cross-functional initiatives, and contribute to regulatory submissions and process enhancements.

Qualifications

• Bachelor's degree required in Mathematics, Statistics, CS, Engineering, Life Science, Public Health, or equivalent.
• 10+ years of experience with the clinical development process and industry standards.
• 7+ years of people or project management experience.
• Advanced SAS programming skills in a clinical environment.
• Demonstrated leadership in developing teams toward common goals.
• Strong influencing, planning, and organizational skills.
• Ability to contribute to functional strategies.
• Strong project management with scope, resource, and financial oversight.
• Experience leading conversations on regulatory submissions.

Responsibilities

• Lead and mentor a group of programmers delivering studies that are outsourced and internal.
• Provide strategic input to cross-functional teams to drive improvements and automation.
• Oversee timely, high-quality deliverables in line with AZ standards and SOPs.
• Contribute to the programming leadership team within Oncology Programming.

Skills

SAS programming

Leadership

People/project management

Regulatory submissions

Cross-functional collaboration

Education

Bachelor's degree (Math/Statistics/CS/Engineering/Life Science/Public Health)

Tools

SAS

CDISC

Regulatory systems

Job description

Are you an experiencedManager and Leader inStatistical Programmingwitha deepknowledge of clinical drug developmentand line management experience? Would you like to be part of a fast-paced and agile global team that hasa directstrategic impact on drug development, empowered and trusted to innovate and experiment? Join us at AstraZenecaOncologyBiometrics toimpacta wide range of engaging projects striving to make a difference for millions of patients. Our Biometrics team consists of Statisticians,Programmersand Information Scientists. We drive and contribute tooptimizedclinical drug development programs and access to information and scientific knowledge management.

We are now offering an exciting opportunity for a dedicated and highly motivated individual to join us in the role asStatistical Programming Director,providing strategic programming leadershipand line managementwithinOncBiometrics and collaborating with global product development teams.

Accountabilities:

This position will work in the Early Oncology Programming group and will be accountable for a large and diverse portfolio of products that cover phase 1 / 2 trials in various mechanisms of action and covering multiple indications within oncology.You willbe responsible formanaging and mentoring a group of programmerswho are in turnaccountable forefficientdelivery onstudiesthat are both outsourced and delivered internally,ensuring high-quality of deliverableswhilecomplying withAZ andindustry standards,SOPsandGxPrequirements.Youwillalsobe part of the larger programming leadership team within oncology programming, andresponsible for various activitiesbeyond clinical trials, such asproving strategic or SMEcontributions oncross-functional teams to deliver continuous improvement, innovation, and automation solutions.

Essential Skills/Experience:

• Minimumbachelor's degree in mathematics(e.g.,Applied Math, Engineering,etc), Statistics, Computer Science, Life Science, PublicHealthor equivalent experience

• Minimum10years of experience with advanced knowledge of the clinical development process and industry standards

• 7+ years people and or project management experience

• Advanced SAS programming skills in a clinical and statistical data environment

• Demonstrated programming leadership capability with ability to develop teams and individuals and lead them towards a common goal

• Demonstrated influencing,planningand organizational skills

• Ability to provide input to functional strategies

• Strong project management skills and experience with scope management, resource management,financial management, projectplanningand resource allocation

• Significant experienceinleadershipcapacity with a focus onidentifying,leading,and advancing talent.

• Experience working in a clinical development organization with a heavy emphasis on support of multiple, ongoing projects

• Thorough understanding of pharmaceutical clinical development (i.e.understanding of statistical concepts, techniques, and clinical trial principles) and ability to manage and lead regulatory submissions.

• Thorough understanding of industry standards such as CDISC and 21CFR Part 11.

• Strong ability to solve problems, recommend process improvements, andexecuteprocess improvements.

• Ability to lead and influence teams

• Excellent verbal and written communication skills in a global environment.

• Proven ability to work with cross functional teams, specifically Data Management, Biostatistics, Epidemiology, Clinical Operations, and Pharmacovigilance toinitiate, lead and execute new initiatives and process improvements.

• Recognize behaviors that align with our values critical to the success of our employees, mission, and businessobjectives.

Desirable Skills/Experience:

• Broad experience, ideally across multiple therapeutic areas and outside of the field of Statistical Programming

• Previousoncology experience, ideallyin bothhemeand solid tumor

• Knowledge / experience using open sourceand/or AIin Statistical Programming

• Experience in regulatory submissions and interactions

• Demonstrated experience designing and implementing business processes

• Willingness and ability to travel

The annual base pay (or hourly rate of compensation) for this position ranges from $168,830.40 - $253,245.60 USD. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

AstraZeneca is an equal opportunity employer that is committed to diversity and inclusion and providing a workplace that is free from discrimination. AstraZeneca is committed to accommodating persons with disabilities. Such accommodation is available on request in respect of all aspects of the recruitment, assessment and selection process and may be requested by emailing [e-mail](opens in new window).

Why AstraZeneca:

Here, ambitious science meets real-world impact. You will work in an environment that pairscutting-edgeplatforms—multi-omics, single-cell and spatial technologies, AI/ML, and advanced imaging with a pipeline that moves decisively from discovery to the clinic. We bring diverse specialists together to ask bold questions, pressure-test ideas, and accelerate progress against some of the hardest-to-treat cancers, valuing kindness alongside ambition so you can stretch your skills while making a tangible difference for patients.

Date Posted

09-Sep-2026

Closing Date

17-Sep-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.