Director, Real World Data & Epidemiology (RWD & EPI) Analytics

Genmab A/S; Princeton (NJ); Hybrid; USD 231,000 - 347,000; Full time

Benefits offered by this job

401(k) Plan: 100% match on the first 6

Health Benefits: Medical, dental and视

Voluntary Plans: Critical illness, etc

Time Off: Paid vacation, holidays, and

Commuter benefits

Tuition reimbursement

Lifestyle Spending Account

Job summary

Genmab is seeking a Director of Real-World Data & Epidemiology Analytics to lead observational studies across diverse RWD sources, translating complex analyses into actionable insights for clinical development and market access.

You will partner with CORE leaders, mentor scientists, and shape governance for study execution while expanding AI-driven analytics and data infrastructure in a fast-paced, collaborative environment.

Qualifications

• PhD or Masters in Epidemiology, Biostatistics, Public Health or related field.
• 10+ years' experience in real-world evidence generation and epidemiology analytics.
• Expertise in observational study design and advanced statistical methods.
• Proficiency in SAS, R, and Python for real-world data.
• Strong communication and stakeholder management.

Responsibilities

• Design, execute, and report observational and epidemiologic studies.
• Assess feasibility and data-source fit for study objectives.
• Conduct survival and economic modeling to support HTA activities.
• Manage study execution including analysis plan, programming, and QC.
• Present results to diverse audiences and translate findings clearly.
• Evolve data infrastructure and governance with cross-functional teams.

Skills

Observational design

Statistical methods

RWD evaluation

SAS/R/Python

Communication

Leadership

Education

PhD or Master in Epidemiology/Biostatistics/Public Health

Tools

SAS

R

Python

Job description

Role

The Director of Real-World Data & Epidemiology (RWD & Epi) Analytics will lead the design, execute, and communicate observational studies using diverse RWD sources. This role combines strategic leadership, deep technical expertise in observational study design and execution, data and analytic infrastructure development, and advanced AI-driven analytics to deliver evidence that informs clinical development, market access, and health-policy decisions. This position reports to Head of RWD & Epi analytics at Center for Outcomes Research, Real World Evidence and Epidemiology (CORE).

Responsibilities

• Collaborate with CORE asset leaders to design, execute, and report on observational and epidemiologic studies in support of assigned assets and indications—from feasibility analyses and protocol development, RWE/Epi methods advice, to data analysis and final reporting.
• Conduct feasibility assessments to match study objectives with optimal RWD sources (claims, EHR, registries, patient-generated data).
• Collaborate with CORE asset leaders to conduct survival and economic modeling to support HTA activities.
• Execute studies by managing table shells, analytic data file, analysis plan, programming, statistical methods, and quality control per regulatory and scientific standards.
• Present study designs, interim analyses, and final results to study team, translating complex findings into actionable insights for both technical and non-technical audiences.
• Evaluate new and emerging data modalities (e.g., claims, EHR, social determinants of health, genomics, biomarkers, clinical notes) for study applicability and integrate them into the evidence-generation framework.
• Lead pilots and scale successful AI applications in routine RWD & Epi analytics.
• Partner with CORE asset leaders to define evidence needs, set realistic timelines, and manage expectations.
• Mentor and coach RWD & Epi scientists and programmers - fostering technical growth in study methods, programming skills, and critical thinking.
• Define and implement standardized processes and governance for study execution, data management, and documentation within the analytic environment.
• Evolve and scale the data and analytics infrastructure - partnering with DD&AI to streamline pipelines, ensure reproducibility, and maintain data security and compliance.
• As a member of the CORE team, contribute to department strategy and objectives as well as represent CORE on key initiatives.

Requirements

• Graduate (PhD or Masters) degree in Epidemiology, Biostatistics, Public Health, or related field.
• 10+ years' experience in real-world evidence generation and epidemiology analytics.
• Demonstrated expertise in observational study design, statistical methods (survival analysis/modeling, regression analysis, IPTW, MAIC, causal inference, etc), and RWD evaluation.
• Hands-on proficiency in statistical programming (SAS, R, Python) on real-world claims/EHR data and AI/ML frameworks.
• Exceptional communication, presentation, and stakeholder-management skills.
• Oncology experience preferred.
• Strong commercial and clinical strategic mindset.
• Demonstrated research accomplishments as evidenced by a history of peer-reviewed publications.
• Ability to work well in a team and cross-functional environment, as well as work independently with limited supervision.
• Ability to work successfully under pressure in a fast-paced environment and with tight timelines.
• Ability to be proactive, enthusiastic and goal oriented.
• Strong communication skills - both oral and written.

Work arrangement

This role offers flexibility to work away from the office for 20%-40% of a typical schedule. Employees may use this work schedule in increments of single days or multiple consecutive days, provided it does not exceed 40% within a 60-day period, and is approved by the hiring manager.

For US based candidates, the proposed salary band for this position is as follows:

$231,280.00---$346,920.00

The actual salary offer will carefully consider a wide range of factors, including your skills, qualifications, experience, and location. Also, certain positions are eligible for additional forms of compensation, such as discretionary bonuses and long-term incentives.

When you join Genmab, you're joining a culture that supports your physical, financial, social, and emotional wellness. Within the first year, regular full-time U.S. employees are eligible for:

• 401(k) Plan: 100% match on the first 6% of contributions
• Health Benefits: Two medical plan options (including HDHP with HSA), dental, and vision insurance
• Voluntary Plans: Critical illness, accident, and hospital indemnity insurance
• Time Off: Paid vacation, sick leave, holidays, and 12 weeks of discretionary paid parental leave
• Support Resources: Access to child and adult backup care, family support programs, financial wellness tools, and emotional well-being support
• Additional Perks: Commuter benefits, tuition reimbursement, and a Lifestyle Spending Account for wellness and personal expenses

Further details on eligibility for compensation and benefits based on role will be provided during the recruitment process

About Genmab

Genmab is an international biotechnology company with a core purpose to improve the lives of patients through innovative and differentiated antibody therapeutics. For 25 years, its hard-working, innovative and collaborative team has invented next-generation antibody technology platforms and harnessed translational, quantitative and data sciences, resulting in a proprietary pipeline including bispecific T-cell engagers, antibody-drug conjugates, next-generation immune checkpoint modulators and effector function-enhanced antibodies. By 2030, Genmab’s vision is to transform the lives of people with cancer and other serious diseases with Knock-Your-Socks-Off (KYSO®) antibody medicines.

Established in 1999, Genmab is headquartered in Copenhagen, Denmark with international presence across North America, Europe and Asia Pacific. For more information, please visit Genmab.com and follow us on LinkedIn and X.

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Please note that if you are applying for a position in the Netherlands, Genmab's policy for all permanently budgeted hires in NL is initially to offer a fixed-term employment contract for a year, if the employee performs well and if the business conditions do not change, renewal for an indefinite term may be considered after the fixed-term employment contract.