Director, Protein Design & Analysis Core

Duke PA; Durham (NC); On-site; USD 190,000 - 250,000; Full time

Job summary

Duke University invites applications for the Research Scholar – Director of the Protein Design and Analysis Core. The role leads a multidisciplinary team focused on de novo protein design, structural characterization, and high‑throughput service delivery to internal and external collaborators.

Candidates should have a Ph.D. in a related field with extensive post‑doctoral or industry experience and a proven leadership record.

Qualifications

• Ph.D. with 8–10 years post-doctoral or industry experience; 3–5 years in leadership/supervisory roles.
• Deep expertise in protein expression/purification and biophysical analysis.
• Strong track record in structural biology methods and computational protein design platforms.

Responsibilities

• Provide visionary scientific and operational leadership for a high-throughput protein design core.
• Oversee a multidisciplinary team and partner with internal programs and external collaborators.
• Drive scientific productivity with peer‑reviewed publications and strategic project management.

Skills

Protein design

Protein expression

Purification

Quality control

Biophysical characterization (SPR, ITC

SEC-MALS

CD

DLS

HDX-MS

X-ray crystallography

Cryo-EM

Python scripting

PyMOL scripting

Education

Ph.D. in Biochemistry/Structural Biology/Biophysics/Computational Biology/Bioengineering

Tools

Rosetta

AlphaFold

ESMFold

Job description

Duke University invites applications for the Research Scholar – Director of the Protein Design and Analysis Core. The role leads a multidisciplinary team focused on de novo protein design, structural characterization, and high‑throughput service delivery to internal and external collaborators.

Candidates should have a Ph.D. in a related field with extensive post‑doctoral or industry experience and a proven leadership record.