Director/Principal, Real-world Data and Healthcare Analytics Lead

705 Lilly USA, LLC; United States; Remote; USD 171,000 - 330,000; Full time

Job summary

Lilly is seeking a senior leader to drive real-world evidence analytics using administrative claims, pharmacy, and medical data. The role combines hands-on programming with strategic oversight, setting standards for analytic quality and reproducibility.

As a senior technical authority, you will mentor scientists, lead rapid-cycle analyses, and collaborate with medical, legal, and regulatory partners to ensure privacy, governance, and impactful insights for US payers and stakeholders.

Qualifications

• Advanced degree in quantitative/health related field with substantial experience in real-world evidence analytics.
• 5+ years hands-on experience with US administrative medical and pharmacy claims data.
• Proficiency in SQL and either R or Python for data harmonization and analysis.

Responsibilities

• Design RWE analyses using claims data, including cohort definitions and lookback logic.
• Program and validate complex analyses from raw data to analysis-ready datasets.
• Set coding standards, QC, validation, and documentation for reproducible analyses.
• Provide expert input on RWD data quality, AI usage, and infrastructure needs.
• Develop AI-enabled workflows and swift, iterative analytic processes.

Skills

RWE analytics

SQL

R

Python

Education

Advanced degree in quantitative/health field

Tools

SQL

R

Python

Job description

At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve. This is hard, urgent, selfless work—but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us.

Purpose: The demand for high-quality health economic and outcomes research (HEOR), health services research (HSR) and real-world evidence (RWE) to support drug development, health technology assessment/access decisions, product differentiation, clinical decision making, and shape the health policy environment continues to increase. The Lilly Research and Evidence Capabilities team within the Health Outcomes and Medical Engagement (HOME) function is looking for talented, energetic, creative, diverse, influential, and collaborative team members to join team.

The real-world data and healthcare analytics lead will be an integral contributor to our evidence generation strategy within the Research and Evidence Capabilities team. This role will serve as the senior technical authority for generating real world evidence from administrative claims data. The lead will use their extensive experience to design and execute rapid-cycle protocol-driven analyses and studies using RWD to match business and strategic research questions.

The role is hands‑on: the lead personally programs and validates complex analyses, sets the analytic standards, methods, and AI-enabled workflows the team relies on. The lead is both the team’s most hands‑on technical expert and the senior reviewer of junior analysts’ work. The lead must be forward‑thinking and innovative, working collaboratively with technology teams to advance RWD platforms and maximize the value of AI and emerging technologies to improve analytic outputs. This is a critical role requiring strong internal partnership, scientific credibility, and the ability to balance adherence to standards and best practices with a need for urgency and rapid innovation.

Note: The hiring manager can customize this job description for the level and desired assignment. It is not to be changed more than 30% for the role.

Primary Responsibilities

Health Economics and Outcomes Research Analysis Lead the design of RWE analyses using administrative claims, pharmacy and medical data, including cohort definitions, enrollment, index‑date and lookback logic, code sets, and fit‑for‑purpose assessment of data sources.

Serve as both technical leader and active contributor: personally program and validate complex analyses from raw RWD through analysis‑ready datasets and results, and set the coding standards the team follows.

Own analytic quality: set and apply standards for code, QC, validation, documentation, and reproducibility, and peer‑review analyses across the team.

Provide expert input on the fit‑for‑purpose assessment of real‑world data (RWD), use of artificial intelligence, and RWD infrastructure needs, Support rapid‑cycle analytic process efficiency, including prioritization, templates, and triage across teams.

Develop AI‑enabled workflows - LLM‑assisted programming, agentic AI, automated QC of analyses and evidence summaries.

Transform RWD sources to analysis ready data sets to enable rapid generation of RWE.

Partner with Medical, Legal, and Regulatory so analyses are designed to support the evidence communications they are intended for.

Ensure analyses meet privacy and data governance requirements (HIPAA, de‑identification, small‑cell suppression, data use agreements).

Mentor and coach research scientists on methods and analytic best practice.

Strategy Applies disease state knowledge, US healthcare industry expertise, and research methods to develop REC team analytics strategy to accelerate insights to US payers and other internal and external stakeholders.

Serves as a strategic partner on lead/core teams across medical, tech and various commercial teams.

Information Dissemination

Collaborate with team members, including field medical team and researchers, to write reports, draft abstracts/posters/manuscripts, create data visualizations, and communicate study/analysis results.

Communicate study results via dashboards, final reports, manuscripts, or oral presentations in group settings, as well as for communicating with key population‑based decision makers (PBDMs) and internal leaders.

Healthcare Industry Domain Knowledge

Understand Lilly relevant disease states and the broader healthcare environment in order to contextualize analytic requests and analytic capability needs. Working knowledge of how claims data are generated, from care delivery and pharmacy dispensing through claims adjudication, and how that shapes data strengths and limitations.

Project Management

Ensures projects and RWD tools meet timelines, budget, and scope by coordinating analytics efforts with cross‑functional Lilly business partners and external collaborators as appropriate.

Minimum Qualification Requirements

Advanced degree (PharmD, MD, PhD, MS, MPH) in a quantitative or health related field (e.g. economics, epidemiology, statistics, actuarial) with significant experience (8+ years with masters or 5+ years with doctorate) with highly relevant experience in RWE analytics.

Demonstrated 5+ years of hands‑on experience working with US and administrative medical and pharmacy claims data (e.g. Marketscan, Optum, Komodo, IQVIA) Advanced proficiency in the use of statistical language and programming software (i.e. SQL and R or Python) to efficiently harmonize and analyze real world data and translate research questions into program specifications.

Other Information/Additional Preferences

Extensive prior data and analytics experience in pharma, managed care or similar healthcare industry. Understanding of medical and pharmacy taxonomy (e.g. NDC, ICD, CPT, HCPCS).

Clinical training or experience Proficient with data visualization and dashboard creation.

Demonstrated ability to influence and collaborate within and across cross‑functional teams primarily residing in US time zones.

Location

US Remote or Indianapolis, IN

Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status. Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees.

Employee Resource Groups

Our current groups include:

• Africa
• Middle East, Central Asia (AMECA)
• Black Employees at Lilly (BE@Lilly)
• Chinese Culture Network (CCN)
• EnAble
• Evolve
• Lilly Indian Network (LIN)
• Organization of Latinx at Lilly (OLA)
• PRIDE (LGBTQ+ Allies)
• Veterans Leadership Network (VLN)
• Women’s Initiative for Leading at Lilly (WILL)

Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

Compensation and Benefits

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is $171,000 - $330,000. Full‑time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance).

In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company‑sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well‑being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).

• Eligibility to participate in a company‑sponsored 401(k)
• pension
• vacation benefits
• eligibility for medical, dental, vision and prescription drug benefits
• flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts)
• life insurance and death benefits
• certain time off and leave of absence benefits
• and well‑being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).

We hope that you seek to join us on our journey as we create medicine and deliver improved outcomes for patients across the globe!

#WeAreLilly At Lilly we strive to ensure our employees are part of a team that cares about them and our shared purpose of making life better for those around the world. How do we do this? We continue to look for ways to include, innovate, accelerate and deliver while maintaining integrity, excellence and respect for people. We hope that you seek to join us on our journey as we create medicine and deliver improved outcomes for patients across the globe! #WeAreLilly