Director, Organoid Systems & Cell Culture

Nick Gilbert Neurofibromatosis Research Institute; Detroit (MI); On-site; USD 180,000 - 260,000; Full time

Job summary

The Nick Gilbert Neurofibromatosis Research Institute (NGNRI) seeks a Director of Cell Culture and Organoids to lead and scale advanced in vitro models, including organoids and assembloids, for discovery and translational research.

','[This role will establish and expand robust culture capabilities for NF1 and related disorders, recruit and mentor staff, and ensure reproducibility and regulatory compliance while collaborating with across-platform leads to integrate organoid systems into

Qualifications

• PhD in stem cell biology, developmental biology, neuroscience, or related discipline.
• Significant experience in stem cell biology, organoids, assembloids, or related model systems.
• Proven track record of developing and implementing complex in vitro models.
• Experience leading or mentoring research teams in academic or industry settings.
• Demonstrated ability to optimize and scale biological systems for reproducibility and throughput.

Responsibilities

• Establish and lead NGNRI’s cell culture and organoid platform, including stem cell derived systems (e.g., cerebroids, assembloids).
• Develop, optimize, and standardize protocols for differentiation, maturation, and maintenance of organoid models.
• Ensure reproducibility, scalability, and robustness of model systems for downstream applications including screening and mechanistic studies.
• Design and implement quality control frameworks for cell lines, differentiation processes, and organoid characterization.
• Recruit, train, and manage a high-performing team of scientists and technical staff.
• Work with platform leads to integrate organoid systems into screening workflows.
• Collaborate with internal and external scientists to adapt models for translational goals.
• Continuously evaluate emerging technologies in stem cell biology and organoid systems.
• Contribute to experimental design, data interpretation, and troubleshooting across programs.
• Maintain meticulous records and ensure data integrity and reproducibility.
• Ensure compliance with biosafety, regulatory, and ethical guidelines.

Skills

Stem cell biology

Organoids

Assembloids

In vitro models

Drug discovery

Leadership

Team management

Education

PhD in stem cell biology

Developmental biology

Neuroscience

Tools

CRISPR

FACS

AI-driven analysis

Job description

The Nick Gilbert Neurofibromatosis Research Institute (NGNRI) seeks a Director of Cell Culture and Organoids to lead and scale advanced in vitro models, including organoids and assembloids, for discovery and translational research.

','[This role will establish and expand robust culture capabilities for NF1 and related disorders, recruit and mentor staff, and ensure reproducibility and regulatory compliance while collaborating with across-platform leads to integrate organoid systems into