Director, Oncology ADC Chemistry & Team Leadership

Novartis Group Companies; Cambridge (MA); Sur place; USD 186 000 - 345 000; Plein temps

Avantages offerts par ce poste

Insurance plans

Retirement plans

Wellbeing resources

Global recognition programs

Hybrid working options

14 weeks parental leave

Résumé du poste

Novartis Group Companies in Cambridge, MA is seeking a Director, Head of Antibody-Drug Conjugate Oncology Chemistry to lead the strategy and execution of ADC programs. You will guide multi-disciplinary teams across chemistry, biology and pharmacology to advance vectorized drug conjugates from discovery toward development milestones.

You will shape portfolio direction, mentor scientists, build strategic partnerships and foster an inclusive, high‑performance culture where bold ideas translate into

Qualifications

• PhD required in Organic Chemistry, Medicinal Chemistry or closely related field.
• 12+ years of pharma/biotech R&D with leadership experience.
• Proven success advancing oncology drug discovery toward clinical development.
• Deep knowledge of ADCs and vectorized drug conjugates.
• Broad understanding of pharmacokinetics, toxicology and pharmacology.
• Demonstrated ability to lead multidisciplinary teams and translate science into strategy.

Responsabilités

• Lead medicinal chemistry strategy for ADC and vectorized programs across oncology portfolio.
• Guide projects from exploration through candidate nomination.
• Build, mentor and develop a high-performing chemistry team.
• Partner with biology, biotherapeutics, PK, safety and process chemistry to advance programs.
• Shape portfolio strategy, prioritization and resourcing in line with oncology goals.
• Identify external collaborations and emerging technologies to strengthen discovery.
• Foster an innovative and inclusive environment amidst complexity and change.

Connaissances

Leadership

Medicinal Chemistry

Organic Chemistry

Pharmacology

Drug Discovery

Cross-functional Leadership

Formation

Doctoral degree in Organic/Medicinal Chemistry

Outils

Computational chemistry tools

Structure-based drug design

Description du poste

Novartis Group Companies in Cambridge, MA is seeking a Director, Head of Antibody-Drug Conjugate Oncology Chemistry to lead the strategy and execution of ADC programs. You will guide multi-disciplinary teams across chemistry, biology and pharmacology to advance vectorized drug conjugates from discovery toward development milestones.

You will shape portfolio direction, mentor scientists, build strategic partnerships and foster an inclusive, high‑performance culture where bold ideas translate into