Director of Statistical Strategy for Infectious Disease

AstraZeneca GmbH; Durham (NC); On-site; USD 120,000 - 180,000; Full time

Job summary

AstraZeneca is seeking a seasoned Statistician to lead strategic statistical thinking across development plans, regulatory strategy, and HTA discussions. You will guide statistical staff, partner with CROs, and represent the function externally to health authorities and conferences.

A strong leadership track record and expertise in trials are required. The role emphasizes mentoring, innovative statistical methods, and cross-study coordination within a global product team.

Qualifications

• MSc/PhD in Statistics, Mathematics (with substantial statistical component) or equivalent.
• Proven track record of independent leadership.
• 5 years of experience in clinical trials is critical for this role.
• Recognized for exemplary technical skills and expert leadership or national recognition as a statistical technical expert.
• Demonstrated ability to provide cross-study support, overseeing, aligning, and providing technical support for multiple studies.

Responsibilities

• Lead the statistical design and strategy to product development plans, preclinical studies, regulatory strategy, health technology assessment, and/or commercial activities as appropriate for the stage of the product.
• Lead the statistical content and ensure quality for study designs, documents, delivery, interpretation, and submission.
• Quantify the benefit, risk, value, and uncertainty of the emerging product profile and communicate these effectively within the team.
• Provide global leadership to others and direct project work delivered by internal and external staff.
• Partner with CROs to ensure delivery to quality and time.
• Represent AstraZeneca externally, including health authorities, advisory boards, conferences, and payer interactions.
• Maintain knowledge of statistical methodology and promote novel approaches.
• Represent statistical strategy at internal governance such as review boards and therapy area leadership teams.
• Mentor/coach and support the technical education and training of Statistics staff.

Skills

Leadership

Clinical trials

Statistical methods

Regulatory knowledge

Cross-study support

Education

Statistics MSc/PhD

Tools

SAS

R

Python

Job description

AstraZeneca is seeking a seasoned Statistician to lead strategic statistical thinking across development plans, regulatory strategy, and HTA discussions. You will guide statistical staff, partner with CROs, and represent the function externally to health authorities and conferences.

A strong leadership track record and expertise in trials are required. The role emphasizes mentoring, innovative statistical methods, and cross-study coordination within a global product team.