Director of Clinical Sciences – Lead Clinical Trial Strategy

Keros Therapeutics, Inc.; Lexington (MA); On-site; USD 200,000 - 241,000; Full time

Job summary

Keros Therapeutics, Inc. is seeking a Director of Clinical Sciences to lead the KER-065 program or other studies from Lexington, MA. This role designs and initiates clinical trials, reviews data, and drives development through regulatory submissions while collaborating with Medical Affairs and cross-functional teams.

Travel up to 20% is required. The candidate will draft clinical development plans, target product profiles, and ensure high data quality across study activities, including CRF data

Qualifications

• Strong understanding of clinical trial design, methodology and regulatory submissions (IND/NDA).
• Experience leading cross-functional teams in a matrixed environment.
• Ability to interpret study results and drive development strategy.
• Excellent communication and leadership skills for collaboration with stakeholders.
• Willingness to travel up to 20% and work in Lexington, MA office.

Responsibilities

• Lead clinical scientist for the KER-065 program or other studies, representing clinical sciences in cross-functional meetings.
• Draft and oversee key documents (protocols, CSRs, IND/CTA/NDA documents) to ensure quality and regulatory readiness.
• Collaborate with biostatistics, clinical development, and other teams for timely data analyses and safety reviews.
• Oversee data quality activities (CRFs, data monitoring, data cleaning) and generate outputs.
• Support clinical development plans, target product profiles, and external scientific communications.
• Contribute to CSR medical content and guide junior team members as needed.

Skills

Clinical development

Leadership

Regulatory submissions

Data analysis

Trial design

Cross-functional collaboration

Education

Doctorate (MD, PhD, PharmD or equivalent)

5+ years clinical development experience

Job description

Keros Therapeutics, Inc. is seeking a Director of Clinical Sciences to lead the KER-065 program or other studies from Lexington, MA. This role designs and initiates clinical trials, reviews data, and drives development through regulatory submissions while collaborating with Medical Affairs and cross-functional teams.

Travel up to 20% is required. The candidate will draft clinical development plans, target product profiles, and ensure high data quality across study activities, including CRF data