Director, Manufacturing Technology Lead - Cell Therapy

AstraZeneca GmbH; Los Angeles (CA); On-site; USD 161,000 - 240,000; Full time

Benefits offered by this job

Incentives

Equity awards

Retirement plans

Paid time off

Health/dental/vision

Job summary

AstraZeneca GmbH in Los Angeles, CA seeks a Director, Manufacturing Technology Lead to guide manufacturing perspectives during new technology evaluations and large-scale deployments. You will bridge Process Sciences, Analytical Technology, and operations to ensure feasible, GMP-compliant adoption across the supply network.

You will drive implementation plans, manage site sequencing, train staff, and contribute to the digital/AI transformation roadmap.

Qualifications

• Bachelor’s degree in engineering (Mechanical or Robotics) or related discipline required; Master’s degree preferred.
• Minimum 10 years in manufacturing technology implementation, tech transfer, or engineering.
• Experience leading full-scale technology deployments in regulated environments.

Responsibilities

• Serve as the primary manufacturing representative in technology evaluation activities; input on operational constraints and GMP considerations.
• Evaluate technologies against manufacturing realities including cleanroom classifications, interfaces, material flows, and scheduling impacts.
• Support PoC evaluations with manufacturing perspective on scalability and integration requirements.
• Develop detailed implementation plans for adoption of new technology at manufacturing sites; include resources, validation, and go-live criteria.
• Coordinate technology deployments across the supply network; establish playbooks and feedback loops for faster site rollouts.
• Support development of digital/AI transformation roadmap with IT and business systems teams.

Skills

Execution-oriented leadership

Cross-functional collaboration

Structured planning

Digital literacy

Bridge development and manufacturing

Education

Bachelor’s degree in engineering (Mechanical or Robotics)

Master’s degree preferred

Job description

About the position, the Director, Manufacturing Technology Lead reports to the Head of Cell Therapy Manufacturing and is responsible for providing manufacturing operational perspective on new technology evaluation.The role supports full-scale implementation of new technology platforms and advanced automation solutions across the Cell Therapy Manufacturing supply network. This role serves as the critical interface between technology development functions and the manufacturing supply sites, ensuring that operational constraints are understood early and that robust implementation plans enable successful adoption at scale. Additionally, this role supports development of the execution pathway from proof-of-concept completion through validated, GMP-compliant deployment at supply sites.

Youwill:

• Serve as the primarymanufacturingrepresentative in technology evaluation activities led by Process Sciences and Analytical Technology; provide input on operational constraints including facility limitations, operator capability requirements, maintenance complexity, scheduling impacts, and GMP compliance considerations that influence technology feasibility and adoption timelines
• Evaluate proposednew technologiesand platforms against the realities of the manufacturing and quality control environment at supply sites including cleanroom classifications, existing equipment interfaces, material flows,resourcemodels, batch scheduling, and regulatory filing implications
• Support proof-of-concept evaluations by providing manufacturing perspective on scalability, operability, integration requirements, and implementation risk; ensure PoC success criteria include manufacturingsite-relevant parameters
• Develop detailed implementation plans for adoption ofnew technologyand platforms at manufacturing supply sites, including resource requirements, training needs, validation strategies,executionpathways, site sequencing, and go-live criteria
• Coordinate technology deployments across thesupplynetwork, defining standard implementation playbooks while accommodating site-specific constraints;establishlessons-learned feedback loops to accelerate sequential site deployments
• Support the development and implementation of the CellTherapyTechnicalOperationsdigital and AI transformation roadmap in collaboration with the Digital and Business Systemsteamsfornew technology
• Supportdevelopment oftraining and competency-building plans that enable operatorsand engineers to effectivelyutilizenew technologiespost-implementation

You have:

• Education:Bachelor’s degree in engineering(Mechanicalor Robotics), or related discipline,Master’sdegree preferred
• Experience: Minimum 10 years in manufacturing technology implementation, tech transfer, or engineering with at least 5 years leading full-scale technology deployments inregulatedenvironments
• Technical Knowledge: Strongexpertisein at least two of: manufacturing,automation/robotics,AI applications,advanced analytical platforms; practical understanding of moving technology from PoC into validated manufacturing operations
• Implementation Experience:Demonstratedtrack recordof leading complex, multi-stakeholder technology implementations from planning through qualification and operational handover in regulated manufacturingenvironments; experience managingnew technologyintroduction alongside existing operations
• Skills: Execution-oriented leadership, cross-functional collaboration, structured planning,digital and tech savvy. The ability to bridge the gap between development innovation and manufacturing operational reality; comfortable operating in a matrixed environment,where,influence and partnership drive outcomes

The annual base pay for this position ranges from $161,000 to $240,000. Our positions offer eligibility for multiple incentives an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

#Onsite #CellTherapy #RoboticsManufacturing

Date Posted

13-Aug-2026

Closing Date

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.